129543-90-4

Basic information

• Product Name: 6,6-dibromopenicillanyl chloride
• CAS NO: 129543-90-4
• Molecular Weight: 377.484
• Mol File: 129543-90-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 6,6-dibromopenicillanyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 6,6-dibromopenicillanyl chloride(129543-90-4)
• EPA Substance Registry System: 6,6-dibromopenicillanyl chloride(129543-90-4)

Safety Data

• Hazardous Substances Data: 129543-90-4(Hazardous Substances Data)

Upstream product

• 24158-88-1 6,6-dibromopenicillanic acid 

Relevant articles and documents

Synthesis and human leukocyte elastase inhibitory evaluation of phosphate triesters and acyl phosphates of penam sulfides and sulfones

The synthesis of 6,6-dibromo-3α-(diphenylphosphate)oxymethyl-2,2-dimethyl penam sulfone (3a), 6α-chloro-3α-(diphenylphosphate)oxymethyl-2,2-dimethyl penam sulfone (3b), benzyl 6α-(diphenyl-phosphate)oxypenicillanate sulfone (4) and 6,6-dibromo-3α-(methylphosphate)carbonyl-2,2-dimethylpenam sulfone (12) are reported. When tested as inhibitors of human leukocyte elastase, the compound 4 proved to be the most active.

REACTIVITY PARAMETERS OF THE METAL ASSISTED 1,2-CLEAVAGE OF PENICILLINS

A straightforward and smooth conversion of penicillins into 1,2-secopenicillanates is described.The thiazolidine ring opening is brought about by the co-operative effect of strong non-nucleophilic bases and thiophilic heavy metal salts.The nature of the l