1300056-90-9

Basic information

• Product Name: 1-[1-(3-diethylaminopropyl)-1H-indol-3-yl]-3-(6-phenylpyridin-2-yl)urea
• Synonyms: 1-[1-(3-diethylaminopropyl)-1H-indol-3-yl]-3-(6-phenylpyridin-2-yl)urea
• CAS NO: 1300056-90-9
• Molecular Weight: 441.576
• Mol File: 1300056-90-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[1-(3-diethylaminopropyl)-1H-indol-3-yl]-3-(6-phenylpyridin-2-yl)urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[1-(3-diethylaminopropyl)-1H-indol-3-yl]-3-(6-phenylpyridin-2-yl)urea(1300056-90-9)
• EPA Substance Registry System: 1-[1-(3-diethylaminopropyl)-1H-indol-3-yl]-3-(6-phenylpyridin-2-yl)urea(1300056-90-9)

Safety Data

• Hazardous Substances Data: 1300056-90-9(Hazardous Substances Data)

Upstream product

• 942-24-5 3-methoxycarbonylindole 
• 1300056-78-3 methyl 1-[3-(tert-butyldimethylsilyloxy)propyl]-1H-indole-3-carboxylate 
• 1300056-85-2 1-(3-diethylaminopropyl)-1H-indole-3-carbonylazide 
• 1300056-83-0 1-(3-diethylaminopropyl)-1H-indole-3-carboxylic acid 
• 1300056-82-9 methyl 1-(3-diethylaminopropyl)-1H-indole-3-carboxylate 
• 39774-25-9 6-phenylpyridin-2-amine 

Relevant articles and documents

The synthesis and evaluation of indolylureas as PKCα inhibitors

PKCα and PKA have crucial but opposing roles in the regulation of calcium handling within myocytes. Identification of compounds that inhibit PKCα, but not PKA, are potential therapeutic targets for the treatment of heart disease. The synthesis of indolylureas are described, and a compound displaying nanomolar inhibition towards PKCα with significant selectivity over PKA has been identified.