13006-19-4Relevant articles and documents
Wheaton,Burton
, p. 25,29, 30, 38, 39 (1977)
THE SYNTHESIS OF ANTIINFLAMMATORY &α-(TRIFLUOROMETHYL)ARYLACETIC ACIDS
Middleton, W. J.,Bingham, E. M.
, p. 561 - 574 (2007/10/02)
Several novel α-trifluoromethylarylacetic acids were synthesized, utilizing chloropentafluoroacetone as the source of the trifluoromethyl group.One of these new acids, the trifluoro-analog (30) of ibuprofen, showed antiinflammatory, analgesic, and ulcerogenic properties similar to ibuprofen.