130284-35-4

Basic information

• Product Name: 2-phenyl-pent-4-en-1-ol
• CAS NO: 130284-35-4
• Molecular Weight: 162.232
• Mol File: 130284-35-4.mol
• Article Data: 26

Chemical Properties

• CAS DataBase Reference: 2-phenyl-pent-4-en-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-pent-4-en-1-ol(130284-35-4)
• EPA Substance Registry System: 2-phenyl-pent-4-en-1-ol(130284-35-4)

Safety Data

• Hazardous Substances Data: 130284-35-4(Hazardous Substances Data)

Upstream product

• 96-09-3 styrene oxide 
• 1802-55-7 diallylzinc 
• 103-82-2 phenylacetic acid 
• 24401-36-3 2-phenyl-4-penten-1-al 
• 101-41-7 benzeneacetic acid methyl ester 
• 1471-03-0 allyl propyl ether 
• 122-78-1 phenylacetaldehyde 
• 14815-73-7 methyl allylphenylacetate 
• 1392108-20-1 O-(2-phenylpent-4-enyl)-N-benzoyl-N-phenylhydroxylamine 
• 1156490-48-0 2-phenyl-1-tosyl-pent-4-enyl N,N-diisopropylcarbamate 
• 182194-86-1 2-phenyl-4-penten-1-yl p-toluenesulfonate 
• 100-42-5 styrene 
• 75-62-7 Bromotrichloromethane 
• 195213-59-3 4-(p-chlorophenyl)-N-(2-phenyl-4-penten-1-oxy)thiazole-2(3H)-thione 

Downstream Products

• 413603-63-1 4-nitro-1-(2-phenyl-pent-4-enyl)-1H-imidazole 
• 413603-28-8 4-phenyl-1-(2-phenyl-pent-4-enyl)-1H-imidazole 
• 413603-64-2 4,5-dichloro-1-(2-phenyl-pent-4-enyl)-1H-imidazole 
• 312631-41-7 N-Butyl-2-(2-phenylpent-4-enyl)amine 
• 312631-34-8 N-butyl-N-chloro-1-phenylpent-4-enylamine 
• 1392108-20-1 O-(2-phenylpent-4-enyl)-N-benzoyl-N-phenylhydroxylamine 

Relevant articles and documents

Carbometalations of simple alkenes with allyldibromoborane.

[formula: see text] The allylboration of alkenes with allyldibromoborane is described. Utilizing an improved methodology for the synthesis of allyldibromoborane, 1,3-dienes, styrene, and even isolated alkenes could be carbometalated in high yield regio- a

syn-Selective Michael Reaction of α-Branched Aryl Acetaldehydes with Nitroolefins Promoted by Squaric Amino Acid Derived Bifunctional Br?nsted Bases

Here we describe a direct access to 2,2,3-trisubstituted syn γ-nitroaldehydes by addition of α-branched aryl acetaldehydes to nitroolefins promoted by a cinchona based squaric acid-derived amino acid peptide. Different α-methyl arylacetaldehydes react with β-aromatic and β-alkyl nitroolefins to afford the Michael adducts in high enantioselectivity and syn-selectivity. NMR experiments and DFT calculations predict the reaction to occur through the intermediacy of E-enolate. The interaction between the substrates and the catalyst follows Pápai's model, wherein an intramolecular H-bond interaction in the catalyst between the NH group of one of the tert-leucines and the squaramide oxygen seems to be key for discrimination of the corresponding reaction transition states.

Highly Enantioselective Catalytic Kinetic Resolution of α-Branched Aldehydes through Formal Cycloaddition with Homophthalic Anhydrides

A new catalytic methodology was developed to promote an efficient one-pot kinetic resolution of racemic aldehydes with selectivity (s*) of up to 91 (99:1 d.r., >99 % ee) in a cycloaddition reaction with enolizable anhydrides to afford dihydroisocoumarin products (a core prevalent in natural products and molecules of medicinal interest) containing three contiguous stereocentres.

COMPOUNDS THAT INHIBIT MCL-1 PROTEIN

Provided herein are myeloid cell leukemia 1 protein (Mcl-1) inhibitors, methods of their preparation, related pharmaceutical compositions, and methods of using the same. For example, provided herein are compounds of Formula I, and pharmaceutically acceptable salts thereof and pharmaceutical compositions containing the compounds. The compounds and compositions provided herein may be used, for example, in the treatment of diseases or conditions, such as cancer.