13031-09-9

Basic information

• Product Name: 2,2-dimethyl-1,3-diphenyl-propan-1-one oxime
• Synonyms: 2,2-dimethyl-1,3-diphenyl-propan-1-one oxime
• CAS NO: 13031-09-9
• Molecular Weight: 253.344
• Mol File: 13031-09-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2,2-dimethyl-1,3-diphenyl-propan-1-one oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2,2-dimethyl-1,3-diphenyl-propan-1-one oxime(13031-09-9)
• EPA Substance Registry System: 2,2-dimethyl-1,3-diphenyl-propan-1-one oxime(13031-09-9)

Safety Data

• Hazardous Substances Data: 13031-09-9(Hazardous Substances Data)

Upstream product

• 13031-08-8 4-phenylpivalophenone 

Downstream Products

• 855267-62-8 2,2-dimethyl-1,3-diphenyl-propan-1-one-imine 
• 1013-88-3 Benzophenone imine 

Relevant articles and documents

Selectfluor-Bu4NI-Mediated C(sp3)-H Oxidation in Aqueous Media: Synthesis of Δ2-Isoxazolines from Oximes

The direct functionalization of an aliphatic C-H bond within a complex molecule through a free-radical pathway is a valuable tool in synthetic chemistry. Herein, we developed an efficient transition-metal-free approach to generate Δ2-isoxazolines from oximes by radical-mediated C(sp3)-H oxidation. Investigation of the mechanism suggested that in the presence of Selectfluor and Bu4NI, the homolysis of the in situ formed O-I bond generated an iminoxyl radical that facilitated subsequent 1,5-H transfer and C(sp3)-H oxidation. The title reaction involves Selectfluor-Bu4NI-mediated C-O bond formation in aqueous media under metal-free conditions. A variety of Δ2-isoxazolines are directly synthesized from oximes by remote intramolecular functionalization of C(sp3)-H bonds.