130328-11-9 Usage
Description
1-(2-cyclohexylethyl)-2-piperazinone, also known as N-cyclohexylethylpiperazinone, is a heterocyclic compound featuring a piperazinone functional group. It is recognized for its potential applications in the pharmaceutical industry, particularly as an intermediate in the synthesis of various organic compounds and drugs. The presence of the cyclohexyl group on the nitrogen atom enhances its utility as a building block in drug development, allowing it to influence the pharmacokinetic properties of the final product. Additionally, it has been noted for its potential anti-anxiety and sedative effects, which makes it a subject of interest for research aimed at developing new treatments for these conditions. Its versatility and pharmacological potential have garnered significant attention in the realms of medicinal chemistry and drug discovery.
Uses
Used in Pharmaceutical Synthesis:
1-(2-cyclohexylethyl)-2-piperazinone is used as an intermediate in the pharmaceutical industry for the synthesis of various organic compounds and drugs. Its cyclohexyl group on the nitrogen atom serves as a valuable building block, enabling the modulation of the pharmacokinetic properties of the final compounds.
Used in Drug Development:
In the field of drug development, 1-(2-cyclohexylethyl)-2-piperazinone is utilized as a key component in the creation of new drugs. Its potential anti-anxiety and sedative effects make it a promising candidate for the development of novel treatments for anxiety disorders and conditions that require sedation.
Used in Medicinal Chemistry:
1-(2-cyclohexylethyl)-2-piperazinone is employed in medicinal chemistry as a versatile compound with potential pharmacological properties. Its unique structure and functional groups make it an attractive target for research and development, with the aim of discovering new drugs and therapies.
Used in Drug Discovery:
Within the domain of drug discovery, 1-(2-cyclohexylethyl)-2-piperazinone is used as a starting point for the exploration of new chemical entities. Its structural features and potential biological activities provide a foundation for the design and synthesis of innovative drug candidates.
Check Digit Verification of cas no
The CAS Registry Mumber 130328-11-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,0,3,2 and 8 respectively; the second part has 2 digits, 1 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 130328-11:
(8*1)+(7*3)+(6*0)+(5*3)+(4*2)+(3*8)+(2*1)+(1*1)=79
79 % 10 = 9
So 130328-11-9 is a valid CAS Registry Number.
130328-11-9Relevant articles and documents
Cyclization-Activated Prodrugs. Basic Esters of 5-Bromo-2'-deoxyuridine
Saari, Walfred S.,Schwering, John E.,Lyle, Paulette A.,Smith, Steven J.,Engelhardt, Edward L.
, p. 2590 - 2595 (2007/10/02)
Some 3'- and 5'-glycyl> esters of 5-bromo-2'-deoxyuridine were prepared and evaluated in vitro as progenitors of the parent alcohol.The sters proved to be relatively stable at low pH but released 5-bromo-2'-deoxyuridine cleanly at rates which were pH and structure dependent.These basic esters are examples of cyclization-activated prodrugs in which generation of active drug is not linked to enzymatic cleavage but rather results from an intramolecular cyclization-elimination reaction.
