130412-44-1Relevant articles and documents
Stereocontrolled Addition Reaction of Organometallics to Chiral α-Keto Amides
Fujisawa, Tamotsu,Ukaji, Yutaka,Funabora, Makoto,Yamashita, Mikio,Sato, Toshio
, p. 1894 - 1897 (1990)
Complementary stereoselection in the addition reaction of several organometallics to chiral benzoylformamide, prepared from benzoylformic acid and (S)-2-(methoxymethyl)pyrrolidine, could be achieved using magnesium- and titanium-based reagents to give different diastereomers of atrolactamide.On the other hand, the reaction of phenyl metallics to the corresponding pyruvamide afforded (S)-atrolactamide.
