130442-55-6

Basic information

• Product Name: 3-tert.butyldiphenylsilyloxy-propionitrile
• Synonyms: 3-tert.butyldiphenylsilyloxy-propionitrile
• CAS NO: 130442-55-6
• Molecular Weight: 323.51
• Mol File: 130442-55-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3-tert.butyldiphenylsilyloxy-propionitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 3-tert.butyldiphenylsilyloxy-propionitrile(130442-55-6)
• EPA Substance Registry System: 3-tert.butyldiphenylsilyloxy-propionitrile(130442-55-6)

Safety Data

• Hazardous Substances Data: 130442-55-6(Hazardous Substances Data)

Upstream product

• 628-22-8 4-hydroxy-1-butanitrile 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 1308265-32-8 C₃₃H₄₆⁽²⁾H₆N₂O₅Si 
• 155504-68-0 5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid α-ethylbenzyl ester 
• 155504-67-9 5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid α-methylbenzyl ester 
• 155504-66-8 5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid benzyl ester 
• 155504-65-7 5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid t.butyl ester 
• 155504-64-6 5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid ethyl ester 
• 155504-63-5 5-hydroxy-3-oxo-7-t.butyldiphenylsilyloxy-heptanoic acid methyl ester 
• 127793-62-8 4-((tert-butyldiphenylsilyl)oxy)butanal 

Relevant articles and documents

Conformations of spermine in adenosine triphosphate complex: The structural basis for weak bimolecular interactions of major cellular electrolytes

Selectively 2H- and 13C-labeled spermines (SPM) were efficiently synthesized and analyzed by NMR spectroscopy to determine the spin-spin coupling constants for six conformationally relevant bonds. SPM that is composed of three alkyl moieties, a butanylene, and two propanylene chains undergoes a conformational change when interacting with multivalent anions (e.g., adenosine triphosphate (ATP), ATP-Mg2+, and tripolyphosphate). Upon interaction with ATP, the C-C bonds, which affect the distance between the neighboring pairs of ammonium groups (i.e., N1/N5 and N5/N5′), increase the population of gauche rotamers by 17-20 % relative to those in the 4 HCl salt of SPM. However, the trend in increments of the gauche conformers for the SPM-ATP complex profoundly differs from that of the spermidine (SPD)-ATP complex. This implies that SPM may preferentially recognize the adenyl group of ATP rather than the tripolyphosphate moiety. This may account for the higher affinity of SPM to ATP-Mg2+ than with that of SPD, which chiefly interacts with β- and I-phosphates and is easily replaced by Mg 2+. These results may provide a clue for the further understanding of the structural basis of polyamine biological functions. Spermines and spin: Spermines (SPM) labeled selectively with 2H and 13C were used to determine the spin-spin coupling constants for six conformationally relevant bonds. SPM revealed diverse conformational changes upon interaction with adenosine triphosphate (ATP), ATP-Mg2+, and tripolyphosphate (TPP, see graph). Copyright