130632-12-1

Basic information

• Product Name: (3R,4R)-3-Amino-4-(4-fluoro-phenyl)-1-(4-methoxy-phenyl)-azetidin-2-one
• Synonyms: (3R,4R)-3-Amino-4-(4-fluoro-phenyl)-1-(4-methoxy-phenyl)-azetidin-2-one
• CAS NO: 130632-12-1
• Molecular Weight: 286.306
• Mol File: 130632-12-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,4R)-3-Amino-4-(4-fluoro-phenyl)-1-(4-methoxy-phenyl)-azetidin-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,4R)-3-Amino-4-(4-fluoro-phenyl)-1-(4-methoxy-phenyl)-azetidin-2-one(130632-12-1)
• EPA Substance Registry System: (3R,4R)-3-Amino-4-(4-fluoro-phenyl)-1-(4-methoxy-phenyl)-azetidin-2-one(130632-12-1)

Safety Data

• Hazardous Substances Data: 130632-12-1(Hazardous Substances Data)

Upstream product

• 130632-07-4 (E)-1-(4-fluorophenyl)-N-(4-methoxyphenyl)methanimine 
• 130632-03-0 1-[(1R,2S,5R)-(-)-(menthyloxycarbonyl)methyl]-2,2,5,5-tetramethyl-2,5-disila-1-azacyclopentane 

Relevant articles and documents

ASYMMETRIC SYNTHESIS OF β-LACTAMS BY CHIRAL ESTER ENOLATE-IMINE CONDENSATION

Asymmetric cyclocondensation of N,N-bis(silyl)glycinates bearing chiral ester moieties with aldimines is found to proceed with extremely high enantioselectivity to give the corresponding chiral β-lactams in good to high yields.It is found that the E/Z-geometry of the chiral ester-enolate is responsible for cis/trans stereochemistry of the β-lactam formed.Effects of various chiral auxiliaries in the ester-enolates on the enantioselectivity of the reactions are examined.