130740-27-1

Basic information

• Product Name: N-diphenylmethylene-L-threonine methyl ester
• Synonyms: N-diphenylmethylene-L-threonine methyl ester
• CAS NO: 130740-27-1
• Molecular Weight: 297.354
• Mol File: 130740-27-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-diphenylmethylene-L-threonine methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: N-diphenylmethylene-L-threonine methyl ester(130740-27-1)
• EPA Substance Registry System: N-diphenylmethylene-L-threonine methyl ester(130740-27-1)

Safety Data

• Hazardous Substances Data: 130740-27-1(Hazardous Substances Data)

Upstream product

• 1013-88-3 Benzophenone imine 
• 39994-75-7 L-threonine methyl ester hydrochloride 

Downstream Products

• 120238-59-7 Methyl (Z)-N-(Diphenylmethylene)-α,β-didehydro-β-methylalaninate 
• 133157-05-8 2,3,4,6-tetra-O-acetyl-β-D-glucopyranoside 
• 133157-06-9 2,3,6,2',3',4',6'-hepta-O-acetyl-β-D-lactoside 
• 120238-58-6 Methyl (E)-N-(Diphenylmethylene)-α,β-didehydro-β-methylalaninate 

Relevant articles and documents

Method for making amino acid glycosides and glycopeptides

A compound of the formula STR1 is disclosed. X is selected from the group consisting of aryl, alkyl, imidate ester, imino ester, amidine, azide, isocyanate, and dithiocarbonate. R' is a group selected from the group consisting of groups containing a hydroxyl moiety, groups containing a protected hydroxyl moiety, and groups containing an O-linked sugar. G is a carbon chain of 0-10 carbons and R is not a methyl group and is a group capable of removal under conditions compatible with glycopeptide synthesis. In a preferred form the compound, R is selected from the group consisting of benzylic or allyl groups and X is CPh2. A method of forming a glycocide from the compound is also disclosed.

O-Glycopeptides: A simple β-stereoselective glycosidation of serine and threonine via a favorable hydrogen bonding pattern

Glycosidation of serine and threonine is promoted by using an intramolecular hydrogen bond to the hydroxyl group.