130798-67-3

Basic information

• Product Name: 1,5-Naphthalenedisulfonicacid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(sulfonylimino)]bis-, tetrasodium salt(9CI)
• CAS NO: 130798-67-3
• Molecular Formula: C32H24 N2 O16 S6 . 4 Na
• Mol File: 130798-67-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1,5-Naphthalenedisulfonicacid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(sulfonylimino)]bis-, tetrasodium salt(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,5-Naphthalenedisulfonicacid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(sulfonylimino)]bis-, tetrasodium salt(9CI)(130798-67-3)
• EPA Substance Registry System: 1,5-Naphthalenedisulfonicacid, 3,3'-[[1,1'-biphenyl]-4,4'-diylbis(sulfonylimino)]bis-, tetrasodium salt(9CI)(130798-67-3)

Safety Data

• Hazardous Substances Data: 130798-67-3(Hazardous Substances Data)

Usage

Chemical Class

Naphthalene sulfonic acids

Appearance

Bright blue color

Usage

Industrial and consumer products, particularly in the textile and paper industries

Purpose

To impart color to fabrics and paper products

Hazardous Nature

Can be harmful if ingested or inhaled

Potential Irritation

May cause irritation to the skin and eyes

Disposal

Important to dispose of properly to prevent environmental contamination

Safety Precautions

Handle with care and follow safety guidelines for handling hazardous chemicals

Upstream product

• 3406-84-6 biphenyl-4,4'-disulfonyl chloride 
• 131-27-1 3-amino-1,5-naphthalenedisulfonic acid 

Relevant articles and documents

Potential anti-AIDS agents. Synthesis and antiviral activity of naphthalenesulfonic acid derivatives against HIV-1 and HIV-2

Certain naphthalenesulfonic acid analogues have been synthesized and evaluated for their inhibitory effects on HIV-1- and HIV-2-induced cytopathogenicity, HIV-1 giant cell formation, and HIV-1 reverse transcriptase (RT) activity. A bis(naphthalenedisulfonic acid) derivative having a biphenyl spacer emerged as the most potent and selective inhibitor of virus-induced cytopathogenicity in MT-4 cells. The ED50 values for this compound were 7.6 and 36 μM for HIV-1 and HIV-2, respectively. No toxicity to the host cells was detected at 98 μM. This compound also inhibited giant cell formation and was superseded in potency by a bis(naphthalenedisulfonic acid) derivative having a flexible decamethylene spacer. In the cell-free RT assay, a long-chain amide derivative exhibited the most inhibition of RT. All the compounds that achieved complete inhibition of virus-induced cytopathogenicity at concentrations not toxic to host cells were derivatives of 4-amino-5-hydroxy-2,7-naphthalenedisulfonic acid. These analogues represent new leads for the development of anti-HIV agents.