1308721-98-3

Basic information

• Product Name: (3Z)-1-isopropyloxycarbonyl-6-[4,5-dimethoxy-2-(methoxymethoxy)-3-methylphenylmethyl]-3-[[4,5-dimethoxy-3-methyl-2-(4-methylphenylsulfonyloxy)phenyl]methylene]-4-(4-methoxyphenylmethyl)piperazine-2,5-dione
• Synonyms: (3Z)-1-isopropyloxycarbonyl-6-[4,5-dimethoxy-2-(methoxymethoxy)-3-methylphenylmethyl]-3-[[4,5-dimethoxy-3-methyl-2-(4-methylphenylsulfonyloxy)phenyl]methylene]-4-(4-methoxyphenylmethyl)piperazine-2,5-dione
• CAS NO: 1308721-98-3
• Molecular Weight: 876.979
• Mol File: 1308721-98-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3Z)-1-isopropyloxycarbonyl-6-[4,5-dimethoxy-2-(methoxymethoxy)-3-methylphenylmethyl]-3-[[4,5-dimethoxy-3-methyl-2-(4-methylphenylsulfonyloxy)phenyl]methylene]-4-(4-methoxyphenylmethyl)piperazine-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: (3Z)-1-isopropyloxycarbonyl-6-[4,5-dimethoxy-2-(methoxymethoxy)-3-methylphenylmethyl]-3-[[4,5-dimethoxy-3-methyl-2-(4-methylphenylsulfonyloxy)phenyl]methylene]-4-(4-methoxyphenylmethyl)piperazine-2,5-dione(1308721-98-3)
• EPA Substance Registry System: (3Z)-1-isopropyloxycarbonyl-6-[4,5-dimethoxy-2-(methoxymethoxy)-3-methylphenylmethyl]-3-[[4,5-dimethoxy-3-methyl-2-(4-methylphenylsulfonyloxy)phenyl]methylene]-4-(4-methoxyphenylmethyl)piperazine-2,5-dione(1308721-98-3)

Safety Data

• Hazardous Substances Data: 1308721-98-3(Hazardous Substances Data)

Upstream product

• 1376220-15-3 (3,4-dimethoxy-2-methylphenoxy)methyl methyl ether 
• 133129-56-3 1,2-dimethoxy-4-(methoxymethoxy)benzene 
• 98-59-9 p-toluenesulfonyl chloride 
• 50827-64-0 3,4-dimethyoxy-2-methylphenol 
• 135-77-3 1,2,4-trimethoxy-benzene 
• 2033-89-8 3,4-dimethoxyphenol 
• 1308721-90-5 4,5-dimethoxy-2-(methoxymethoxy)-3-methylbenzaldehyde 
• 108-23-6 isopropyl chloroformate 
• 1308721-86-9 2-hydroxy-3-methyl-4,5-dimethoxybenzaldehyde 
• 1308721-97-2 (3Z)-1-acetyl-6-[4,5-dimethoxy-2-(methoxymethoxy)-3-methylphenylmethyl]-3-{[4,5-dimethoxy-3-methyl-2-(4-methylphenylsulfonyloxy)phenyl]methylene}piperazine-2,5-dione 
• 1308722-20-4 4,5-dimethoxy-3-methyl-2-[(4-methylphenylsulfonyl)oxy]benzaldehyde 
• 1308721-94-9 1,4-diacetyl-3-[(4,5-dimethoxy-2-methoxymethoxy-3-methylphenyl)methyl]piperazine-2,5-dione 

Relevant articles and documents

Chemistry of renieramycins. Part 12: An improved total synthesis of (±)-renieramycin G

An improved total synthesis of (±)-renieramycin G (1g) from readily available 2-hydroxy-3-methyl-4,5-dimethoxybenzaldehyde (7) in 21 steps (6.3% overall yield) is described. The synthesis features the concise construction of a pentacyclic framework using the stereoselective Pictet-Spengler type cyclization reaction of lactam (25) with ethyl diethoxyacetate, followed by the base-catalyzed epimerization of the C-1 stereo center of aldehyde (30a). The results of cytotoxicity studies are also presented.