1309100-65-9Relevant articles and documents
Small molecule antagonists of the urokinase (uPA): Urokinase receptor (uPAR) interaction with high reported potencies show only weak effects in cell-based competition assays employing the native uPAR ligand
De Souza, Melissa,Matthews, Hayden,Lee, Jodi A.,Ranson, Marie,Kelso, Michael J.
, p. 2549 - 2556 (2011/06/11)
Binding of the urokinase-type plasminogen activator (uPA) to its cell-surface-bound receptor uPAR and upregulation of the plasminogen activation system (PAS) correlates with increased metastasis and poor prognosis in several tumour types. Disruptors of th