131-69-1 Usage
Description
PHTHALYLSULFACETAMIDE, also known as Phthalylsulphacetamide, is a synthetic compound with antibacterial properties. It is a derivative of sulfonamide, a class of antimicrobial agents, and is characterized by its phthalic acid and acetamide groups. PHTHALYLSULFACETAMIDE exhibits broad-spectrum antimicrobial activity against various bacteria, making it a valuable component in pharmaceutical formulations.
Uses
Used in Pharmaceutical Industry:
PHTHALYLSULFACETAMIDE is used as an antibacterial agent for treating bacterial infections. Its broad-spectrum activity allows it to target a wide range of bacteria, making it effective against various infections. It is commonly used in the form of ointments and creams for topical application, particularly for skin infections.
Used in Antimicrobial Formulations:
PHTHALYLSULFACETAMIDE is used as an active ingredient in antimicrobial formulations, such as ointments and creams, to combat bacterial infections. Its effectiveness in inhibiting bacterial growth makes it a valuable component in these formulations, helping to reduce inflammation and promote healing.
Brand names:
Talsigel (Bristol-Myers Squibb) and Thalamyd (Schering) are some of the brand names under which PHTHALYLSULFACETAMIDE is marketed. These products are specifically formulated to provide targeted antibacterial action for the treatment of various infections.
Purification Methods
It is prepared by hydrolysis of N-acetamidosulfophenylpthalimide by boiling for 3hours in 15% aqueous KOH followed by treatment with Norit, filtration and acidification with AcOH. Crystallise the phthalamide from hot H2O or EtOH [Jain et al. J Indian Chem Soc 24 174 1947]. Itis antibacterial.[Beilstein 14 III 2073.]
Check Digit Verification of cas no
The CAS Registry Mumber 131-69-1 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 1,3 and 1 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 131-69:
(5*1)+(4*3)+(3*1)+(2*6)+(1*9)=41
41 % 10 = 1
So 131-69-1 is a valid CAS Registry Number.
InChI:InChI=1/C16H14N2O6S/c1-10(19)18-25(23,24)12-8-6-11(7-9-12)17-15(20)13-4-2-3-5-14(13)16(21)22/h2-9H,1H3,(H,17,20)(H,18,19)(H,21,22)
131-69-1Relevant articles and documents
Solid-solid reaction between sulfacetamide and phthalic anhydride
Weng,Parrott
, p. 1059 - 1063 (1984)
Thermal and kinetic data for the solid-state addition reaction of sulfacetamide and phthalic anhydride are presented. A compaction method was used so that the influence of some pharmaceutical parameters (compressional pressure, particle size, concentration, and temperature) on the reaction kinetics could be observed.