1311254-63-3 Usage
Description
(R/S)-3-(benzyloxycarbonylamino)-5-methylhexanoic acid is a chiral chemical compound derived from the amino acid valine, featuring a benzyloxycarbonyl protecting group attached to the amino group. This molecule exists in two mirror-image forms, known as R and S configurations, and is widely utilized in the synthesis of peptides and pharmaceuticals, as well as in medicinal chemistry for drug development and biochemical research.
Uses
Used in Pharmaceutical Synthesis:
(R/S)-3-(benzyloxycarbonylamino)-5-methylhexanoic acid is used as a key intermediate in the pharmaceutical industry for the synthesis of various peptides and pharmaceuticals. Its unique structure and the presence of the benzyloxycarbonyl protecting group make it a valuable building block in the development of new drugs.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (R/S)-3-(benzyloxycarbonylamino)-5-methylhexanoic acid serves as a versatile compound for the development of novel drugs. Its chiral nature allows for the exploration of the different biological activities of its R and S enantiomers, potentially leading to the discovery of more effective and selective therapeutic agents.
Used in Biochemical Research:
(R/S)-3-(benzyloxycarbonylamino)-5-methylhexanoic acid is also employed as a research tool in biochemical studies. Its structural features and reactivity make it suitable for investigating various biological processes and interactions, contributing to a deeper understanding of molecular mechanisms and the development of targeted therapies.
Used in Drug Development:
As a chiral molecule with two distinct enantiomers, (R/S)-3-(benzyloxycarbonylamino)-5-methylhexanoic acid is used in drug development to explore the different pharmacological properties of its R and S forms. This can lead to the identification of more potent and selective drug candidates, ultimately improving the efficacy and safety of new therapeutics.
Check Digit Verification of cas no
The CAS Registry Mumber 1311254-63-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,1,2,5 and 4 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1311254-63:
(9*1)+(8*3)+(7*1)+(6*1)+(5*2)+(4*5)+(3*4)+(2*6)+(1*3)=103
103 % 10 = 3
So 1311254-63-3 is a valid CAS Registry Number.
1311254-63-3Relevant articles and documents
The kinetic resolution of oxazinones by alcoholysis: access to orthogonally protected β-amino acids
Cronin, Sarah A.,Connon, Stephen J.
supporting information, p. 7348 - 7352 (2021/09/07)
The catalytic, alcoholytic kinetic resolution of oxazinones is reported. A novel, stereochemically dense cinchona alkaloid-based catalyst can facilitate the highly enantiodiscriminatory (Sup to 101) ring-opening of oxazinones equipped with electrophilic aryl units to generate orthogonally protected β-amino acids for the first time.
Synthesis of enantiopure free and N-benzyloxycarbonyl-protected 3-substituted homotaurines from naturally occurring amino acids
Zheng, Yongpeng,Xu, Jiaxi
, p. 5197 - 5206 (2014/07/08)
Enantiopure N-benzyloxycarbonyl-protected and free 3-substituted homotaurines were synthesized from naturally occurring amino acids via N-benzyloxycarbonyl protection, Arndt-Eistert homologation, reduction, esterification with thioacetic acid, and oxidation with performic acid. The current method is a convenient, practical, and salt-free method for the synthesis of enantiopure 3-substituted homotaurine with moderate to good yields.
