1312023-63-4 Usage
Functional groups
Nitro group (-NO2), Fluorine atom (-F), Trifluoroethyl group (CF3-CH2-)
Chemical class
Nitrobenzene derivative
Structure
A benzene ring with a fluorine atom at the 1st position, a trifluoroethyl group at the 2nd position, and a nitro group at the 3rd position
Applications
Organic synthesis, pharmaceutical research, building block for pharmaceuticals, agrochemicals, and fine chemicals
Reactivity
Due to the presence of functional groups, it can undergo various chemical reactions
Toxicity
Considered toxic and may have harmful effects on human health and the environment
Handling precautions
Handle with care, use appropriate safety measures, and avoid inhalation, ingestion, or skin contact
Physical state
Likely a solid or liquid at room temperature (depending on the specific conditions)
Solubility
Soluble in organic solvents such as dichloromethane, acetone, and ethanol, but may have limited solubility in water due to the presence of fluorine atoms and the nitro group
Check Digit Verification of cas no
The CAS Registry Mumber 1312023-63-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,3,1,2,0,2 and 3 respectively; the second part has 2 digits, 6 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1312023-63:
(9*1)+(8*3)+(7*1)+(6*2)+(5*0)+(4*2)+(3*3)+(2*6)+(1*3)=84
84 % 10 = 4
So 1312023-63-4 is a valid CAS Registry Number.
1312023-63-4Relevant articles and documents
Cu-mediated chemoselective trifluoromethylation of benzyl bromides using shelf-stable electrophilic trifluoromethylating reagents
Kawai, Hiroyuki,Furukawa, Tatsuya,Nomura, Yoshinori,Tokunaga, Etsuko,Shibata, Norio
supporting information; experimental part, p. 3596 - 3599 (2011/09/16)
Copper-mediated chemoselective trifluoromethylation at the benzylic position by the use of shelf-stable electrophilic trifluoromethylating reagents 3 in good to high yields under mild conditions is described for the first time. The generality of this trifluoromethylation for a wide variety of benzyl bromides facilitates the rapid creation of structural diversity of medicinal candidates in drug discovery.
