131216-18-7Relevant articles and documents
Folate analogues. 34. Synthesis and antitumor activity of non-polyglutamylatable inhibitors of dihydrofolate reductase
Abraham,McGuire,Galivan,Nimec,Kisliuk,Gaumont,Nair
, p. 222 - 227 (2007/10/02)
Five analogues of methotrextate (MTX), 10-deazaaminopterin (10-DAM), and 10-ethyl-10-deazaaminopterin (10-EDAM) in which the glutamate moiety was replaced by either a γ-methyleneglutamate or β-hydroxyglutamate were synthesized and evaluated for their anti