1312996-59-0Relevant articles and documents
Regioselective Suzuki coupling of dihaloheteroaromatic compounds as a rapid strategy to synthesize potent rigid combretastatin analogues
Theeramunkong, Sewan,Caldarelli, Antonio,Massarotti, Alberto,Aprile, Silvio,Caprioglio, Diego,Zaninetti, Roberta,Teruggi, Alessia,Pirali, Tracey,Grosa, Giorgio,Tron, Gian Cesare,Genazzani, Armando A.
, p. 4977 - 4986 (2011/10/01)
Combretastatin A-4 (CA-4) is a potent tubulin depolymerizing agent able to inhibit tumor growth and with antivascular effects. Although it is in clinical trials, the search for novel analogues that may display better/different features is still ongoing. I