13142-09-1 Usage
Description
1-(4-bromophenyl)-3-(3-chlorophenyl)urea is a synthetic organic compound characterized by the presence of a urea molecule with a 4-bromophenyl group and a 3-chlorophenyl group attached to it. 1-(4-bromophenyl)-3-(3-chlorophenyl)urea holds potential applications in the pharmaceutical and agrochemical industries due to its unique structure and properties.
Uses
Used in Pharmaceutical Industry:
1-(4-bromophenyl)-3-(3-chlorophenyl)urea is used as a building block for the synthesis of more complex molecules with potential therapeutic applications. Its unique structure, including the bromine and chlorine atoms, may confer specific chemical and physical properties that make it suitable for the development of new drugs.
Used in Agrochemical Industry:
In the agrochemical sector, 1-(4-bromophenyl)-3-(3-chlorophenyl)urea may be utilized as a starting material for the creation of compounds with pesticidal or herbicidal properties. 1-(4-bromophenyl)-3-(3-chlorophenyl)urea's structure and properties could be harnessed to develop novel agrochemicals that address various agricultural challenges.
Used in Medicinal Chemistry Research:
1-(4-bromophenyl)-3-(3-chlorophenyl)urea's structure and properties make it an interesting candidate for further research and development in the field of medicinal chemistry. Scientists may explore its potential to interact with biological targets, leading to the discovery of new therapeutic agents.
Used in Organic Synthesis:
1-(4-bromophenyl)-3-(3-chlorophenyl)urea's unique structure also makes it a valuable intermediate in organic synthesis, where it can be used to create a variety of other complex organic molecules with diverse applications across different industries.
Check Digit Verification of cas no
The CAS Registry Mumber 13142-09-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,4 and 2 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 13142-09:
(7*1)+(6*3)+(5*1)+(4*4)+(3*2)+(2*0)+(1*9)=61
61 % 10 = 1
So 13142-09-1 is a valid CAS Registry Number.
InChI:InChI=1/C13H10BrClN2O/c14-9-4-6-11(7-5-9)16-13(18)17-12-3-1-2-10(15)8-12/h1-8H,(H2,16,17,18)
13142-09-1Relevant articles and documents
Synthesis, in vitro urease inhibitory activity, and molecular docking studies of thiourea and urea derivatives
Bano, Bilquees,Kanwal,Khan, Khalid Mohammed,Lodhi, Arif,Salar, Uzma,Begum, Farida,Ali, Muhammad,Taha, Muhammad,Perveen, Shahnaz
, p. 129 - 144 (2018/06/20)
The current study deals with the synthesis of urea and thiourea derivatives 1–37 which were characterized by various spectroscopic techniques including FAB-MS, 1H-, and 13C NMR. The synthetic compounds were subjected to urease inhibitory activity and compounds exhibited good to moderate urease inhibitory activity having IC50 values in range of 10.11–69.80 μM. Compound 1 (IC50 = 10.11 ± 0.11 μM) was found to be most active and even better as compared to the standard acetohydroxamic acid (IC50 = 27.0 ± 0.5 μM). A limited structure–activity relationship (SAR) was established and the compounds were also subjected to docking studies to confirm the binding interactions of ligands (compounds) with the active site of enzyme.
