13145-56-7

Basic information

• Product Name: 1,4-Butanedione, 1,4-bis(4-methylphenyl)-
• CAS NO: 13145-56-7
• Molecular Formula: C18H18O2
• Molecular Weight: 266.34
• Mol File: 13145-56-7.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: 1,4-Butanedione, 1,4-bis(4-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,4-Butanedione, 1,4-bis(4-methylphenyl)-(13145-56-7)
• EPA Substance Registry System: 1,4-Butanedione, 1,4-bis(4-methylphenyl)-(13145-56-7)

Safety Data

• Hazardous Substances Data: 13145-56-7(Hazardous Substances Data)

Usage

Physical State

Yellow liquid

Odor

Strong, sweet, and fruity

Natural Occurrence

Commonly found in fruits such as berries and cherries

Primary Uses

a. Production of fragrances and flavorings
b. Intermediate in organic synthesis
c. Raw material for the production of pharmaceuticals and pesticides

Toxicity

Low toxicity, making it relatively safe for use in consumer products and industrial applications

Upstream product

• 42289-03-2 (Z)-1,4-Bis(4-methylphenyl)but-2-ene-1,4-dione 
• 66864-60-6 1,4-bis(4-methylphenyl)-2-butyne-1,4-dione 
• 543-20-4 succinoyl dichloride 
• 108-88-3 toluene 
• 13581-83-4 ω-(Methylsulphinyl)-p-methylacetophenon 
• 54731-27-0 1-p-methylphenyl-1-trimethylsiloxyethene 
• 15982-67-9 1,4-di-p-tolyl-butane-1,4-diol 
• 116858-55-0 (1Z,3Z)-N,N,N',N'-Tetramethyl-1,4-di-p-tolyl-buta-1,3-diene-1,4-diamine 
• 77-77-0 Divinyl sulfone 
• 104-87-0 4-methyl-benzaldehyde 
• 37032-34-1 2-fluoro-1-(4-methylphenyl)ethanone 
• 122-00-9 para-methylacetophenone 
• 108-30-5 succinic acid anhydride 
• 4294-57-9 para-methylphenylmagnesium bromide 

Downstream Products

• 21399-23-5 2,5-di(4-methylphenyl)-1H-pyrrole 
• 23460-42-6 Z,Z-1,4-Bis-(p-tolyl)-1,4-bis-(ethylmercapto)-buta-1,3-dien 
• 222158-46-5 C₂₂H₂₆ 
• 222158-41-0 C₂₂H₂₆ 
• 222158-45-4 C₂₂H₂₆ 
• 57196-75-5 2,5-bis(p-tolyl)furan 
• 82366-98-1 2,5-bis(4'-methylphenyl)thiophene 
• 1189240-14-9 (-)-(1S,4S)-1,4-di(4-methylphenyl)-1,4-butanediol 
• 1205612-20-9 2,5-di-p-tolyl-N-[2-(benzylamino)phenyl]pyrrole 
• 1205612-05-0 2,5-di-p-tolyl-N-(2-mercaptophenyl)pyrrole 
• 51678-13-8 2,5-di-p-toluoylselenophene 
• 222158-71-6 endo,cis-1,4-bis(4-methylphenyl)-2,3-dimethylbicyclo<2.2.0>hexane 
• 222158-44-3 C₂₂H₂₆ 
• 5465-41-8 ditoluylethylene 

Relevant articles and documents

Unexpected formation of 4,4-dimethyl-1,2-disubstituted-dicarbonyl cyclopentanes from ketone enolate anions and 1,3-diiodo-2,2-dimethylpropane

Cyclic 1,4-dicarbonyl compounds can be easily obtained by mixing a solution of aryl methyl or alkyl methyl ketone enolate anions with 1,3-diiodo-2,2-dimethylpropane in DMSO. This represents the first example of dimerization of ketone enolate anions using a simple diiodoalkane as a reagent followed by subsequent double alkylation with bis-iodide yielding a cyclopentane adduct. This methodology allows the use of a simple potassium tert-butoxide as a base at room temperature for the formation of three C-C bonds resulting in a relatively complex five-membered ring diketone structure under transition-metal-free conditions.

Asymmetric hydrogenation of 1,4-diketones: facile synthesis of enantiopure 1,4-diarylbutane-1,4-diols

Owing to the biological significance and great synthetic value of 1,4-diarylbutane-1,4-diols and their derivatives, increasingly considerable attention has been paid to developing effective synthetic methods for chiral 1,4-diarylbutane-1,4-diols. We herei

Synthesis of 2,2,5-Trisubstituted 2 H-Pyrroles and 2,3,5-Trisubstituted 1 H-Pyrroles by Ligand-Controlled Site-Selective Dearomative C2-Arylation and Direct C3-Arylation

Palladium-catalyzed site-selective dearomative C2-arylation of 2,5-diaryl-1H-pyrroles with aryl chlorides was accomplished, and a series of 2,2,5-triaryl-2H-pyrroles were synthesized. In addition, the site selectivity of the reaction was switched by simply changing the ligand, and the direct C3-arylated 2,3,5-triaryl-1H-pyrroles were prepared. The obtained 2,2,5-triaryl-2H-pyrroles could be further transformed into 2,2,5,5-tetraarylpyrrolidines.