131470-58-1Relevant articles and documents
Preparation of 5-Substituted 2-Mercapto-1-methylimidazoles. Direct Metalation of 2-Mercapto-1-methylimidazole
Phillips, Brian T.,Claremon, David A.,Varga, Sandor L.
, p. 761 - 763 (2007/10/02)
2-Mercapto-1-methylimidazole (1) is directly metalated with tert-butyllithium in tetrahydrofuran to give the 5,S-dianion 2.Reaction of the dianion 2 with a series of electrophiles gives regioselectively 5-substituted 2-mercapto-1-methylimidazoles 4, 5 and