13159-74-5

Basic information

• Product Name: Benzenemethanamine, 4-chloro-N-(4-chlorophenyl)-
• CAS NO: 13159-74-5
• Molecular Formula: C13H11Cl2N
• Molecular Weight: 252.143
• Mol File: 13159-74-5.mol
• Article Data: 36

Chemical Properties

• CAS DataBase Reference: Benzenemethanamine, 4-chloro-N-(4-chlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenemethanamine, 4-chloro-N-(4-chlorophenyl)-(13159-74-5)
• EPA Substance Registry System: Benzenemethanamine, 4-chloro-N-(4-chlorophenyl)-(13159-74-5)

Safety Data

• Hazardous Substances Data: 13159-74-5(Hazardous Substances Data)

Upstream product

• 1751-80-0 4-chloro-N-(4-chlorobenzylidene)aniline 
• 71-23-8 propan-1-ol 
• 1751-80-0 (E)-4-chloro-N-(4-chlorobenzylidene)benzenamine 
• 106-47-8 4-chloro-aniline 
• 104-83-6 1-Chloro-4-(chloromethyl)benzene 
• 104-86-9 4-chlorobenzylamine 
• 104-88-1 4-chlorobenzaldehyde 
• 39193-06-1 4,4'-dichlorobenzanilide 
• 614-30-2 N-methyl-N-phenyl-benzenemethanamine 
• 38318-45-5 (Z)-4-chloro-N-(4-chlorobenzylidene)aniline 
• 128886-84-0 p-Chlorophenyl p-nitrobenzenesulphonate 
• 80-33-1 chlorofensone 
• 80-38-6 fenson 
• 599-89-3 4-chlorophenyl p-toluenesulfonate 

Downstream Products

• 109937-24-8 N-(4-chlorobenzyl)-N-(4-chlorophenyl)benzamide 
• 21923-45-5 6-chloro-2-(4-chlorophenyl)-4-phenylquinoline 
• 1240273-18-0 N-allyl-N-(4-chlorobenzyl)-4-chloroaniline 
• 1751-80-0 4-chloro-N-(4-chlorobenzylidene)aniline 
• 104-88-1 4-chlorobenzaldehyde 
• 55245-36-8 C₁₄H₁₀Cl₃NO 

Relevant articles and documents

Zinc-catalyzed reduction of imines by triethylsilane

Low-cost zinc is employed as a catalyst along with triethylsilane (TES) in a simple, straightforward, chemoselective reduction of various aldimines and ketimines to the corresponding secondary amines at room temperature and pressure.

New benzamide derivatives and their nicotinamide/cinnamamide analogs as cholinesterase inhibitors

In this study, a total of 18 new benzamide/ nicotinamide/ cinnamamide derivative compounds were designed and synthesized for the first time (except B1 and B5) by conventional and microwave irradiation methods. The chemical structures of the synthesized co

Ruthenium N-Heterocyclic Carbene Complexes for Chemoselective Reduction of Imines and Reductive Amination of Aldehydes and Ketones

Chemoselective reduction of imines to secondary amines is catalyzed efficiently by tethered and untethered, half-sandwich ruthenium N-heterocyclic carbene (NHC) complexes at room temperature. The untethered Ru-NHC complexes are more efficient as catalysts for the reduction of aldimines and ketimines than the tethered complexes. Using the best untethered complex as a catalyst, electronic and steric demands on the reaction was probed using a series of imines. Chemoselectivity of the catalyst towards imine reduction was tested by performing inter and intramolecular competitive reactions in a variety of ways. The catalyst exhibits a very high TON and TOF under anaerobic conditions.

Catalyst- And solvent-free efficient access to: N -alkylated amines via reductive amination using HBpin

A sustainable approach which works under catalyst- and solvent-free conditions for the synthesis of structurally diverse secondary amines has been uncovered. This one-pot protocol works efficiently at room temperature and is compatible with a wide range of sterically and electronically diverse aldehydes and primary amines. Notably, this simple process offers scalability, excellent functional group tolerance, chemoselectivity, and is also effective at the synthesis of biologically relevant molecules. This journal is