13177-41-8 Usage
Description
3-(Dimethyloctadecylazaniumyl)propane-1-sulfonate, also known as 3-(N,N-Dimethyloctadecylammonio)propanesulfonate, is a zwitterionic surfactant characterized by its unique structure that contains both positive and negative charges within the same molecule. This property makes it particularly useful in various applications, such as membrane solubilization studies, where it can interact with biological membranes without causing significant disruption. Additionally, its lack of UV light absorption makes it an ideal choice for applications that require spectrophotometric analysis of proteins, as it does not interfere with the measurements.
Uses
Used in Pharmaceutical Industry:
3-(Dimethyloctadecylazaniumyl)propane-1-sulfonate is used as an extraction agent for the solubilization and extraction of drugs, such as erythromycin, from the aqueous phase. Its ability to form an organic mixed micellar phase in combination with bis(2-ethylhexyl) sulfosuccinate sodium salt (AOT) enhances the extraction performance and allows for the evaluation of parameters affecting erythromycin solubilization.
Used in Membrane Solubilization Studies:
In the field of biochemistry and molecular biology, 3-(Dimethyloctadecylazaniumyl)propane-1-sulfonate serves as a valuable tool for membrane solubilization. It is used as a surfactant to study the properties and functions of biological membranes, such as protein-lipid interactions and membrane protein structure, without causing significant disruption to the membrane integrity.
Used in Spectrophotometric Analysis:
3-(Dimethyloctadecylazaniumyl)propane-1-sulfonate is utilized as a non-interfering agent in spectrophotometric analysis of proteins. Its lack of UV light absorption ensures that it does not interfere with the measurements, allowing for accurate and reliable results in various protein studies.
Check Digit Verification of cas no
The CAS Registry Mumber 13177-41-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,1,7 and 7 respectively; the second part has 2 digits, 4 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 13177-41:
(7*1)+(6*3)+(5*1)+(4*7)+(3*7)+(2*4)+(1*1)=88
88 % 10 = 8
So 13177-41-8 is a valid CAS Registry Number.
InChI:InChI=1/C23H49NO3S/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-21-24(2,3)22-20-23-28(25,26)27/h4-23H2,1-3H3
13177-41-8Relevant articles and documents
Synthesis, characterization and surface properties of series sulfobetaine surfactants
Qu, Guangmiao,Cheng, Jiecheng,Wei, Jijun,Yu, Tao,Ding, Wei,Luan, Huoxin
, p. 31 - 35 (2011)
A series of surface active sulfo-propane betaines and sulfo-butane betaines were synthesized with high yields by the reaction of an appropriate N,N-dimethyl alkylamine with an excess of 1,3-propane sultone and 1,4-butane sultone. The structures were characterized by 1H-NMR spectroscopy and elemental analysis. The micellar properties of these compounds were determined by surface tension methods. Surface tension measurements also provide information about the dependence of the surface tension at the CMC (γcmc), pC20 (negative logarithm of the surfactant molar concentration C20 required to reduce the surface tension by 20 mN/m), the surface excess (Γmax) at air/solution interface, the minimum area per surfactant molecule at the air solution interface (A).
