13217-97-5Relevant articles and documents
Synthesis of Pyrrole Derivatives Mediated by Dicobalthexacarbonyl
Wang, Jeng-Long,Ueng, Chuen-Her,Yeh, Ming-Chang P.
, p. 2823 - 2826 (1995)
Addition of α- and β-amino acid derivatives to the cobalt stabilized propargylic cation 2 gives dicobalthexacarbonyl complexes with an amino acid derivative at the propargyl position.Oxidation of the resulting complexes with Fe(III) produces propargyl ami
Unveiling the Biocatalytic Aromatizing Activity of Monoamine Oxidases MAO-N and 6-HDNO: Development of Chemoenzymatic Cascades for the Synthesis of Pyrroles
Scalacci, Nicoló,Black, Gary W.,Mattedi, Giulio,Brown, Nicola L.,Turner, Nicholas J.,Castagnolo, Daniele
, p. 1295 - 1300 (2017/08/09)
A chemoenzymatic cascade process for the sustainable production of pyrroles has been developed. Pyrroles were synthesized by exploiting the previously unexplored aromatizing activity of monoamine oxidase enzymes (MAO-N and 6-HDNO). MAO-N/6-HDNO whole cell biocatalysts are able to convert 3-pyrrolines into pyrroles under mild conditions and in high yields. Moreover, MAO-N can work in combination with the ruthenium Grubbs catalyst, leading to the synthesis of pyrroles from diallylamines/-anilines in a one-pot cascade metathesis-aromatization sequence.
β-selective C-H arylation of pyrroles leading to concise syntheses of lamellarins C and I
Ueda, Kirika,Amaike, Kazuma,Maceiczyk, Richard M.,Itami, Kenichiro,Yamaguchi, Junichiro
supporting information, p. 13226 - 13232 (2015/03/30)
The first general β-selective C-H arylation of pyrroles has been developed by using a rhodium catalyst. This C-H arylation reaction, which is retrosynthetically straightforward but results in unusual regioselectivity, could result in de novo syntheses of
