132959-43-4

Basic information

• Product Name: (-)-(3R,7aS)-3-Phenyl-5-oxo-7a-butyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole
• Synonyms: (-)-(3R,7aS)-3-Phenyl-5-oxo-7a-butyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole
• CAS NO: 132959-43-4
• Molecular Weight: 259.348
• Mol File: 132959-43-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (-)-(3R,7aS)-3-Phenyl-5-oxo-7a-butyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole(CAS DataBase Reference)
• NIST Chemistry Reference: (-)-(3R,7aS)-3-Phenyl-5-oxo-7a-butyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole(132959-43-4)
• EPA Substance Registry System: (-)-(3R,7aS)-3-Phenyl-5-oxo-7a-butyl-2,3,5,6,7,7a-hexahydropyrrolo<2,1-b>oxazole(132959-43-4)

Safety Data

• Hazardous Substances Data: 132959-43-4(Hazardous Substances Data)

Upstream product

• 56613-80-0 D-2-phenylglycinol 
• 4316-44-3 4-oxooctanoic acid 

Downstream Products

• 137869-79-5 (R)-4-Allyl-4-benzyloxycarbonylamino-octanoic acid methyl ester 
• 137869-92-2 (R)-2-Allyl-2-butyl-5-oxo-pyrrolidine-1-carboxylic acid benzyl ester 
• 137869-73-9 (R)-5-Allyl-5-butyl-1-((R)-2-hydroxy-1-phenyl-ethyl)-pyrrolidin-2-one 
• 137869-73-9 (S)-5-Allyl-5-butyl-1-((R)-2-hydroxy-1-phenyl-ethyl)-pyrrolidin-2-one 
• 116830-34-3 (-)-N-<2-(1-Hydroxy-2(R)-phenylethyl)>-5(R)-butyl-2-pyrrolidine 

Relevant articles and documents

A Simple Asymmetric Synthesis of 2-Substituted Pyrrolidines and 5-Substituted Pyrrolidinones

An efficient procedure for the preparation of the title compounds in high enantiomeric purity has been realized starting from 3-acylpropionic acids.Stereoselective reduction of chiral bicyclic lactams 2a-h, prepared from the corresponding γ-keto acid and

A Simple Asymmetric Synthesis of 2-Substituted Pyrrolidines from 3-Acylpropionic Acids

The title compounds have been prepared from 3-acylpropionic acids 2 and (-)-R-phenylglycinol in a three-step sequence in >98percent enantiomeric excess.The R group in 2 ultimately becomes the 2-substituent in the chiral pyrrolidine.