13315-65-6Relevant articles and documents
Halogenated (F, Cl) 1,3-benzodiazoles, 1,2,3-benzotriazoles, 2,1,3-benzothia(selena)diazoles and 1,4-benzodiazines inducing Hep2 cell apoptosis
Prima, Darya O.,Vorontsova, Elena V.,Makarov, Arkady G.,Makarov, Alexander Yu.,Bagryanskaya, Irina Yu.,Mikhailovskaya, Tatiana F.,Slizhov, Yuri G.,Zibarev, Andrey V.
, p. 439 - 442 (2017/10/05)
The title compounds synthesized from halogenated arene-1,2-diamines revealed, together with the latter, cytotoxicity towards the Hep2 (laryngeal epidermoid carcinoma) cells. The cytotoxicity was high and was accompanied by pronounced apoptotic activity at