133218-33-4

Basic information

• Product Name: N-(3-Phenylbutyryl)pyrrolidine-2-thione
• CAS NO: 133218-33-4
• Molecular Weight: 247.361
• Mol File: 133218-33-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3-Phenylbutyryl)pyrrolidine-2-thione(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3-Phenylbutyryl)pyrrolidine-2-thione(133218-33-4)
• EPA Substance Registry System: N-(3-Phenylbutyryl)pyrrolidine-2-thione(133218-33-4)

Safety Data

• Hazardous Substances Data: 133218-33-4(Hazardous Substances Data)

Upstream product

• 2295-35-4 pyrrolidin-2-thione 
• 51552-98-8 3-phenylbutanoyl chloride 

Downstream Products

• 133218-46-9 N-(3'-Phenylbut-3'-enoyl)pyrrolidine-2-thiol 
• 133218-45-8 5-Mercapto-4-methyl-4-phenyl-1-azabicyclo<3.3.0>octan-2-one 

Relevant articles and documents

Photochemical δ-Hydrogen Abstraction from Acyclic and Semicyclic Monothioimides

Photochemical δ-hydrogen abstraction from acyclic and semicyclic monothioimides have been studied.Photolysis of acyclic monothioimides possessing a benzylic hydrogen atom at the δ-position gave γ-lactams, via a 1,5-diradical intermediate, accompanied by thioamides were generated by γ-hydrogen abstraction.Irradiation of the five-membered semicyclic monothioimide, N-(3-phenylpropionyl)pyrrolidine-2-thione, yielded 5-mercapto-4-phenyl-1-azabicyclooctan-2-one.For N-(3-phenylbutyryl)pyrrolidine-2-thione, disproportionation, involving 1,6-hydrogen migration, was the main path.Photolysis of the six-membered semicyclic monothioimide, N-(3-phenylbutyryl)piperidine-2-thione, gave an unsaturated thiol, via a 1,4-hydrogen shift of a 1,5-diradical intermediate, accompanied by cyclisation product and piperidine-2-thione.