133368-88-4

Basic information

• Product Name: 2-(N-methyl-o-anisidino)-ethanol
• CAS NO: 133368-88-4
• Molecular Weight: 181.235
• Mol File: 133368-88-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(N-methyl-o-anisidino)-ethanol(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(N-methyl-o-anisidino)-ethanol(133368-88-4)
• EPA Substance Registry System: 2-(N-methyl-o-anisidino)-ethanol(133368-88-4)

Safety Data

• Hazardous Substances Data: 133368-88-4(Hazardous Substances Data)

Upstream product

• 72955-82-9 N-[2-(2-methoxyphenoxy)ethyl]methylamine 
• 10541-78-3 2-methoxy-N-methylaniline 
• 107-07-3 2-chloro-ethanol 

Downstream Products

• 77901-22-5 4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazine 

Relevant articles and documents

Direct Substitution of Aromatic Ethers by Lithium Amides. A New Aromatic Amination Reaction

Reaction of lithiated dialkylamines with methoxy aromatics in refluxing THF leads to products resulting from a direct ipso-substitution.Especially with lithiated secondary amines high conversions and selectivities are achieved.Sulfonyl-substituted aromatics react equally well, but halogenated aromatics give rise to side-products arising from a competing pathway via aryne intermediates.The scope and mechanistic implications of this novel nucleophilic amination reaction are described.