1337426-46-6Relevant articles and documents
2-Hydroxy-3-[(S)-prolinamido]pinanes as novel bifunctional organocatalysts for asymmetric aldol reactions in aqueous media
Siyutkin, Dmitry E.,Kucherenko, Alexander S.,Frolova, Larisa L.,Kuchin, Alexander V.,Zlotin, Sergei G.
experimental part, p. 1320 - 1324 (2011/11/29)
Novel (S)-prolinamides with stereoisomeric 2-hydroxy-3-aminopinane units have been synthesized. In the presence of (1R,2R,3S,5R)-2-hydroxy-3-[(S)- prolinamido]pinane (5 mol %) cyclic ketones reacted with (hetero-)aromatic aldehydes in aqueous media to aff