133871-04-2

Basic information

• Product Name: Benzeneacetic acid, (2E)-3-phenyl-2-propenyl ester
• CAS NO: 133871-04-2
• Molecular Formula: C17H16O2
• Molecular Weight: 252.313
• Mol File: 133871-04-2.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, (2E)-3-phenyl-2-propenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, (2E)-3-phenyl-2-propenyl ester(133871-04-2)
• EPA Substance Registry System: Benzeneacetic acid, (2E)-3-phenyl-2-propenyl ester(133871-04-2)

Safety Data

• Hazardous Substances Data: 133871-04-2(Hazardous Substances Data)

Upstream product

• 300-57-2 allylbenzene 
• 103-82-2 phenylacetic acid 
• 112654-60-1 (E)-cinnamyl bromoacetate 
• 1619239-43-8 (E)-1-(2-(cinnamyloxy)-2-oxoethyl)tetrahydro-1H-thiophen-1-ium tetraphenylborate 
• 201230-82-2 carbon monoxide 
• 1666-17-7 benzaldehyde p-toluenesulfonylhydrazone 
• 4407-36-7 (2E)-3-phenyl-2-propen-1-ol 
• 101-41-7 benzeneacetic acid methyl ester 
• 4392-24-9 Cinnamyl bromide 
• 114-70-5 sodium phenylacetate 
• 1797-74-6 allyl phenylacetate 
• 960-16-7 tributylphenylstannane 

Downstream Products

• 618907-47-4 cinnamyl 2-diazo-2-phenylacetate 
• 103-82-2 phenylacetic acid 
• 133871-28-0 (2S,3R)-diphenyl-4-pentenoic acid 
• 133871-28-0 (2R,3S)-diphenyl-4-pentenoic acid 

Relevant articles and documents

Benzyne-Mediated Esterification Reaction

A benzyne-mediated esterification of carboxylic acids and alcohols under mild conditions has been realized, which is made possible via a selective nucleophilic addition of carboxylic acid to benzyne in the presence of alcohol. After a subsequent transesterification with alcohol, the corresponding esters can be produced efficiently. This benzyne-mediated protocol can be used on the modification of Ibuprofen, cholesterol, estradiol, and synthesis of nandrolone phenylpropionate. In addition, benzyne can also be used to promote lactonization and amidation reaction.

Metal-free carbon-carbon cross-couplings between the ion pairs in sulfonium tetraphenylborates

A series of sulfonium tetraphenylborates can be readily prepared by the metathesis of sulfonium halides with sodium tetraphenylborates. After heating at 120-150 °C, the sulfonium tetraphenylborates can smoothly undergo the cross-couplings between the tetraphenylborate anions and the sulfonium cations in the absence of a metal catalyst. For carbonylmethyl-, benzyl-, and allylsulfoniums, the corresponding carbonylmethyl-phenyl, benzyl-phenyl, and allyl-phenyl cross-coupling products can be obtained in 22-76% yields. An interionic electron-transfer mechanism for this cross-coupling reaction is proposed.

Zwitterionic salts as mild organocatalysts for transesterification

(Chemical Equation Presented) The exothermic reaction of 3,5-bis(trifluoromethyl)phenyl or 4-nitrophenyl isothiocyanate with 4-pyrrolidinopyridine (PPY) gave the corresponding arylaminothiocarbonylpyridinium salts in quantitative yields. These novel zwitterionic salts were effective as organocatalysts for the transesterification reaction of an equimolar mixture of methyl carboxylates and alcohols in hydrocarbons such as heptane and octane under azeotropic reflux conditions with the removal of methanol. In sharp contrast, PPY was inert as a catalyst under the same reaction conditions.