13389-07-6 Usage
Main properties
1. Chemical name: 2-amino-8-(hydroxyamino)-9-pentofuranosyl-3,9-dihydro-6H-purin-6-one
2. Common name: 2-Amino-8-Δ-ribosyl-9H-purin-6-ol
3. Classification: Purine nucleoside
4. Function: Essential for storing and transmitting genetic information
5. Occurrence: Found naturally in DNA and RNA
6. Biological role: Crucial for protein synthesis and energy transfer within cells
7. Therapeutic use: Used in the treatment of viral infections and cancer
Specific content
Consists of a ribose sugar linked to a purine base
Plays a vital role in various biological processes
Used as a therapeutic agent for hepatitis B and C, as well as cancer
Important for the structure and function of DNA and RNA
Check Digit Verification of cas no
The CAS Registry Mumber 13389-07-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,3,8 and 9 respectively; the second part has 2 digits, 0 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13389-07:
(7*1)+(6*3)+(5*3)+(4*8)+(3*9)+(2*0)+(1*7)=106
106 % 10 = 6
So 13389-07-6 is a valid CAS Registry Number.
13389-07-6Relevant articles and documents
8-Substituted guanosine and 2'-deoxyguanosine derivatives as potential inducers of the differentiation of Friend erythroleukemia cells
Lin,Cheng,Ishiguro,Sartorelli
, p. 1194 - 1198 (2007/10/02)
A variety of 8-substituted guanosine and 2'-deoxyguanosine derivatives were synthesized and tested as inducers of the differentiation of Friend murine erythroleukemia cells in culture. The most active agents in the guanosine series were 8-substituted -N(CH3)2, -NHCH3, -NH2, -OH, and -SO2CH3, which caused 68, 42, 34, 33, and 30% of erythroleukemia cells to attain benzidine positivity, a functional measure of maturation, at concentrations of 5, 1, 0.4, 5, and 5 mM, respectively. The 8-OH derivative of the 2'-deoxyguanosine series produced comparable activity, causing 62% benzidine-positive cells at a level of 0.2 mM. These findings indicate that 8-substituted analogues of guanosine and 2'-deoxyguanosine have the potential to terminate leukemia cell proliferation through conversion to end-stage differentiated cells.
