1338926-78-5

Basic information

• Product Name: 5-(3-bromo-4-fluorophenyl)-3-(3,4,5-trichloro-phenyl)-3-(trifluoromethyl)-3,4-dihydro-2H-pyrrole
• CAS NO: 1338926-78-5
• Molecular Weight: 489.522
• Mol File: 1338926-78-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-(3-bromo-4-fluorophenyl)-3-(3,4,5-trichloro-phenyl)-3-(trifluoromethyl)-3,4-dihydro-2H-pyrrole(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(3-bromo-4-fluorophenyl)-3-(3,4,5-trichloro-phenyl)-3-(trifluoromethyl)-3,4-dihydro-2H-pyrrole(1338926-78-5)
• EPA Substance Registry System: 5-(3-bromo-4-fluorophenyl)-3-(3,4,5-trichloro-phenyl)-3-(trifluoromethyl)-3,4-dihydro-2H-pyrrole(1338926-78-5)

Safety Data

• Hazardous Substances Data: 1338926-78-5(Hazardous Substances Data)

Upstream product

• 1350374-95-6 (2E)-4,4,4-trifluoro-3-(3,4,5-trichlorophenyl)buta-2-enoic acid 
• 1350375-00-6 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 5-(3-bromo-4-fluoro-phenyl)-3-(3,4,5-trichlorophenyl)-3-(trifluoromethyl)-3,4-dihydro-2H-pyrrole-4-carboxylate 
• 1350476-12-8 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl 2-(3-bromo-4-fluorophenyl)-4-(3,4,5-tri-chlorophenyl)-4-(trifluoromethyl)-3,4-dihydro-2H-pyrrole-3-carboxylate 
• 1350374-96-7 (1R,2S,5R)-2-isopropyl-5-methylcyclohexyl (2E)-4,4,4-trifluoro-3-(3,4,5-trichloro-phenyl)but-2-enoate 
• 1338926-74-1 1-(3-bromo-4-fluorophenyl)-4,4,4-trifluoro-3-(nitromethyl)-3-(3,4,5-trichlorophenyl)-butan-1-one 
• 1338926-79-6 1,2,3-trichloro-5-(3,3,3-trifluoro-1-nitroprop-1-en-2-yl) benzene 
• 1338926-70-7 N-{5-[4,4,4-trifluoro-3-(nitromethyl)-3-(3,4,5-trichloro-phenyl)butanoyl]-2,3-dihydro-1H-inden-1-yl}propanamide 
• 1338926-81-0 N-(5-acetyl-2,3-dihydro-1H-inden-1-yl)propanamide 
• 1338926-80-9 tert-butyl N-(5-acetylindan-1-yl)carbamate 
• 1296879-69-0 1,1,1-trifluoro-3-nitro-2-(3,4,5-trichlorophenyl)propan-2-ol 
• 158401-00-4 1-(3,4,5-trichloro-phenyl)-2,2,2-trifluoro-ethanone 
• 185122-63-8 5-bromo-2,3-dihydro-1H-inden-1-one oxime 
• 903555-95-3 (±)-tert-butyl (5-bromo-2,3-dihydro-1H-inden-1-yl)carbamate 
• 34598-49-7 5-Bromo-1-indanone 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF 5-SUBSTITUTED 3-ARYL-3-(TRIFLUOROMETHYL)-3,4-DIHYDRO-2H-PYRROLES

The present invention relates to a process for the manufacturing of 5-substituted 3-aryl-3-(trifluoro-methyl)-3,4-dihydro-2H-pyrroles of formula (I) which comprises the following steps: (i) reacting a compound of formula (II) with a isonitrile compound of formula (III) in the presence of a metal catalyst to obtain compounds of formula (IV) (ii) isomerizing compounds of formula (IV) to obtain compounds of formula (V) and (iii) reacting the dihydropyrrole compound of formula (V) under acidic conditions, to obtain compounds of formula (I), wherein X, n, Z, Y, and T are as defined in the description.