134201-15-3

Basic information

• Product Name: Pyrido[4,3-d]pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-phenyl-
• CAS NO: 134201-15-3
• Molecular Formula: C13H13N3O
• Molecular Weight: 227.266
• Mol File: 134201-15-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Pyrido[4,3-d]pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrido[4,3-d]pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-phenyl-(134201-15-3)
• EPA Substance Registry System: Pyrido[4,3-d]pyrimidin-4(1H)-one, 5,6,7,8-tetrahydro-2-phenyl-(134201-15-3)

Safety Data

• Hazardous Substances Data: 134201-15-3(Hazardous Substances Data)

Upstream product

• 849777-03-3 C₂H₄O₂*C₁₃H₁₃N₃O 
• 3939-01-3 methyl 1-benzyl-4-oxopiperidine-3-carboxylate hydrochloride 
• 1670-14-0 benzamidine monohydrochloride 
• 1047-48-9 6-benzyl-2-phenyl-5,6,7,8-tetrahydro-3H-pyrido<4,3-d>pyrimidin-4-one 
• 71486-53-8 methyl 4-oxo-3-piperidinecarboxylate hydrochloride 
• 618-39-3 benzamidin 

Downstream Products

• 134200-90-1 N-(2,6-Dimethyl-phenyl)-2-(4-oxo-2-phenyl-3,5,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidin-6-yl)-acetamide 
• 109229-00-7 6-[4-(4-Fluoro-phenyl)-4-oxo-butyl]-2-phenyl-5,6,7,8-tetrahydro-3H-pyrido[4,3-d]pyrimidin-4-one 
• 17037-08-0 2-phenyl-3H-pyrido<4,3-d>pyrimidin-4-one 
• 134200-92-3 N-(2,6-Dichloro-phenyl)-2-(4-oxo-2-phenyl-3,5,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidin-6-yl)-acetamide 
• 134200-94-5 N-(4-Methoxy-phenyl)-3-(4-oxo-2-phenyl-3,5,7,8-tetrahydro-4H-pyrido[4,3-d]pyrimidin-6-yl)-propionamide 
• 849777-41-9 C₁₈H₁₃N₅ 
• 849777-04-4 C₁₃H₈ClN₃ 

Relevant articles and documents

QUINAZOLINE DERIVATIVES AS MEDICAMENTS

Quinazoline derivatives have the formula (I) or the pharmaceutically acceptable salts thereof; wherein each of Z5, Z6, Z7 and Z8 is N or CH and wherein one or two Z5, Z6, Z7 and Z8 are N and wherein two adjacent Z positions cannot be N; wherein m and n are each independently 0-3; wherein R1 is independently OH, SH, NH2, OR, SR, NHR, halo or R-halide; wherein two adjacent R1 groups may be joined to form an aliphatic hetero cycle ring of 5-6 members; wherein R2 is independently R, halo, R-halide, OR-halide, NH2, CONH2 or CONHR; wherein R is optionally substituted C1-C12 alkyl, C1-C12 alkenyl, C1-C12 alkynyl, or aryl C1-C12 alkyl, containing 0-4 heteroatoms in place of a carbon in the carbon backbone, where the optional substituents are =O, =N, or OH; and wherein R3 is H or CH3. Such compounds are useful in pharmaceutical compositions and methods of treating conditions characterized by enhanced TGFβ activity.

Saturated heterocycles, part 172. Synthesis of 2,6-disubstituted-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine derivatives

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