134404-52-7 Usage
Description
Seocalcitol, also known as EB 1089, is a synthetic vitamin D analog that is 50-200 times more potent than calcitriol in inhibiting cell proliferation and differentiation. It has reduced calcemic activity compared to calcitriol and has been shown to promote tumor regression in vitro by inducing apoptosis.
Uses
Used in Pharmaceutical Industry:
Seocalcitol is used as an active pharmaceutical ingredient for the development of drugs targeting cancer treatment. Its potent anti-cancer properties make it a promising candidate for the treatment of various malignancies.
Used in Cancer Research:
Seocalcitol is used as a research tool in androgen receptor-targeted therapy for breast cancer. Its ability to inhibit cell proliferation and induce apoptosis makes it a valuable compound for studying the mechanisms of cancer progression and developing novel therapeutic strategies.
Used in Drug Development:
Seocalcitol is used as a lead compound in the development of new drugs with improved efficacy and reduced side effects. Its potent anti-cancer activity and reduced calcemic activity make it an attractive candidate for the development of next-generation cancer therapies.
Check Digit Verification of cas no
The CAS Registry Mumber 134404-52-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,4,4,0 and 4 respectively; the second part has 2 digits, 5 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 134404-52:
(8*1)+(7*3)+(6*4)+(5*4)+(4*0)+(3*4)+(2*5)+(1*2)=97
97 % 10 = 7
So 134404-52-7 is a valid CAS Registry Number.
InChI:InChI=1/C30H46O3/c1-6-30(33,7-2)18-9-8-11-21(3)26-15-16-27-23(12-10-17-29(26,27)5)13-14-24-19-25(31)20-28(32)22(24)4/h8-9,11,13-14,18,21,25-28,31-33H,4,6-7,10,12,15-17,19-20H2,1-3,5H3/b11-8+,18-9+,23-13-,24-14+/t21-,25-,26-,27+,28+,29-/m1/s1
134404-52-7Relevant articles and documents
Siaud calciferol method for the synthesis of
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, (2019/02/02)
The invention discloses a synthesis method of seocalcitol. (S)-2-(IR,7AR)-4-(tert-butyldimethylsilyl ether)-7a-methyl-octahydro-1H-indene-1-yl) propionaldehyde and (E)-6-(diphenylphosphine)-3-ethylhexyl-4-alkene-3-alcohol are taken as raw materials and ar