13481-67-9 Usage
Description
2-[(2,3-dimethylphenyl)amino]benzonitrile is a chemical compound with the formula C15H13N. It is a white solid with a molecular weight of 219.27 g/mol. This nitrile derivative features a nitrile group (–C≡N) and a benzene ring with an amino group (–NH2) attached. Its chemical properties and structure make it valuable in the production of various compounds with diverse applications in the fields of medicine, biology, and materials science.
Uses
Used in Pharmaceutical Industry:
2-[(2,3-dimethylphenyl)amino]benzonitrile is used as a building block for the synthesis of various pharmaceuticals and organic compounds. Its unique structure and chemical properties contribute to the development of new drugs and therapeutic agents.
Used in Research and Development:
In the field of research and development, 2-[(2,3-dimethylphenyl)amino]benzonitrile is used as a reagent in organic synthesis. It aids in the creation of novel compounds and contributes to the advancement of scientific knowledge in organic chemistry.
Used in Materials Science:
2-[(2,3-dimethylphenyl)amino]benzonitrile is also utilized in materials science for the production of various compounds with specific properties. Its versatility and reactivity make it a valuable component in the development of new materials with potential applications in various industries.
Check Digit Verification of cas no
The CAS Registry Mumber 13481-67-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,4,8 and 1 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 13481-67:
(7*1)+(6*3)+(5*4)+(4*8)+(3*1)+(2*6)+(1*7)=99
99 % 10 = 9
So 13481-67-9 is a valid CAS Registry Number.
13481-67-9Relevant articles and documents
Visible-Light- And PPh3-Mediated Direct C-N Coupling of Nitroarenes and Boronic Acids at Ambient Temperature
Manna, Kartic,Ganguly, Tanusree,Baitalik, Sujoy,Jana, Ranjan
supporting information, p. 8634 - 8639 (2021/11/01)
We present here a metal-free, visible-light- and triphenylphosphine-mediated intermolecular, reductive amination between nitroarenes and boronic acids at ambient temperature without any photocatalyst. Mechanistically, a slow reduction of nitroarenes to a nitroso and, finally, a nitrene intermediate occurs that leads to the amination product with concomitant 1,2-aryl/-alkyl migration from a boronate complex. A wide range of nitroarenes underwent C-N coupling with aryl-/alkylboronic acids providing high yields.
Aminocyanation by the addition of N-CN bonds to arynes: Chemoselective synthesis of 1,2-bifunctional aminobenzonitriles
Rao, Bin,Zeng, Xiaoming
, p. 314 - 317 (2014/01/23)
An efficient aminocyanation by the direct addition of aryl cyanamides to arynes is described, enabling incorporation of highly useful amino and cyano groups synchronously via cleavage of inert N-CN bonds, affording synthetically useful 1,2-bifunctional aminobenzonitriles. The postsynthetic functionalization of the aminocyanation products allows diverse formation of synthetically important derivatives such as drug molecule Ponstan and fused heterocycles.
