135042-28-3

Basic information

• Product Name: [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol
• CAS NO: 135042-28-3
• Molecular Formula: C₁₀H₁₄N₆O
• Molecular Weight: 234.2578
• Mol File: 135042-28-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 534.8°C at 760 mmHg
• Flash Point: 277.2°C
• Density: 1.77g/cm³
• Vapor Pressure: 2.88E-12mmHg at 25°C
• Refractive Index: 1.871
• CAS DataBase Reference: [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol(CAS DataBase Reference)
• NIST Chemistry Reference: [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol(135042-28-3)
• EPA Substance Registry System: [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol(135042-28-3)

Safety Data

• Hazardous Substances Data: 135042-28-3(Hazardous Substances Data)

Usage

Description

[(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol is a chemical compound characterized by a purine ring attached to a pyrrolidin-2-ylmethyl group. The purine ring contains an amino group at the 6th position and a hydroxymethyl group attached to the pyrrolidin-2-yl moiety. [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol is a derivative of purine and is known for its potential applications in pharmaceutical research and drug development. Its structural similarity to nucleic acid bases and potential biological activity make it a promising candidate for the treatment of various medical conditions, including cancer and viral infections. [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol's stereochemistry, defined by the (2R,4R) configuration, significantly impacts its biological properties and interactions with other molecules, making it a chemically and biologically significant compound with potential therapeutic applications.

Uses

Used in Pharmaceutical Research and Drug Development:
[(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol is used as a key compound in pharmaceutical research and drug development for its potential applications in treating various medical conditions. Its structural similarity to nucleic acid bases and potential biological activity make it a valuable asset in the development of new therapeutic agents.
Used in Cancer Treatment:
In the field of oncology, [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol is used as a potential therapeutic agent for the treatment of various types of cancer. Its structural features and biological activity may contribute to the development of novel cancer treatments.
Used in Viral Infection Treatment:
[(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol is also used as a potential therapeutic agent for the treatment of viral infections. Its interaction with nucleic acid bases and other biological molecules may provide insights into the development of antiviral drugs.
Used in Chemical Synthesis:
In the chemical industry, [(2R,4R)-4-(6-amino-9H-purin-9-yl)pyrrolidin-2-yl]methanol is used as a starting material or intermediate in the synthesis of various complex organic compounds, particularly those with potential pharmaceutical applications. Its unique structure and reactivity make it a valuable component in the development of new chemical entities.

Upstream product

• 135042-26-1 N-(tert-butoxycarbonyl)-O-<(4-methoxyphenyl)diphenylmethyl>-cis-4-(6-amino-9H-purin-9-yl)-D-prolinol 
• 906065-74-5 5-(tert-butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidin-3-ol 
• 906065-75-6 toluene-4-sulfonic acid 5-(tert-butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidin-3-yl ester 
• 77449-99-1 (2R,4R)-2-ethoxycarbonyl-4-hydroxypyrrolidine hydrochloride 
• 116143-06-7 4-(acetyloxy)-1-<(4-methylphenyl)sulfonyl>-D-proline ethyl ester 
• 116143-05-6 allo-1-(4-tolylsulfonyl)-4-<<(4-methylphenyl)sulfonyl>oxy>-D-proline ethyl ester 
• 116143-08-9 (2R,4S)-2-(Hydroxymethyl)-4-hydroxy-1-(4-tolylsulfonyl)pyrrolidine 
• 77449-94-6 (2R,4R)-4-hydroxypyrrolidine-2-carboxylic acid hydrochloride 
• 51-35-4 4R-4-hydroxyproline 
• 77450-03-4 (2R,4S)-tert-butyl 4-hydroxy-2-(hydroxymethyl)pyrrolidine-1-carboxylate 
• 135042-21-6 N-(tert-butoxycarbonyl)-O-<(4-methoxyphenyl)diphenylmethyl>-trans-4-hydroxy-D-prolinol 
• 135042-22-7 N-(tert-butoxycarbonyl)-O-<(4-methoxyphenyl)diphenylmethyl>-cis-4-(6-chloro-9H-purin-9-yl)-D-prolinol 
• 135042-12-5 (4R)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline 
• 114676-69-6 (2R,4R)-1-tert-butyl 2-methyl 4-hydroxypyrrolidine-1,2-dicarboxylate 

Relevant articles and documents

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