1350759-56-6Relevant articles and documents
SPIRO ISOXAZOLINE COMPOUNDS AS SSTR5 ANTAGONISTS
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Page/Page column 162; 163, (2011/12/04)
Substituted spirocyclic amines of structural formula (I) are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, Metabolic Syndrome, depression, and anxiety.