135241-33-7

Basic information

• Product Name: (3R,5R,8aR)-5-Benzo[1,3]dioxol-5-ylmethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile
• Synonyms: (3R,5R,8aR)-5-Benzo[1,3]dioxol-5-ylmethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile
• CAS NO: 135241-33-7
• Molecular Weight: 362.428
• Mol File: 135241-33-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3R,5R,8aR)-5-Benzo[1,3]dioxol-5-ylmethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (3R,5R,8aR)-5-Benzo[1,3]dioxol-5-ylmethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile(135241-33-7)
• EPA Substance Registry System: (3R,5R,8aR)-5-Benzo[1,3]dioxol-5-ylmethyl-3-phenyl-hexahydro-oxazolo[3,2-a]pyridine-5-carbonitrile(135241-33-7)

Safety Data

• Hazardous Substances Data: 135241-33-7(Hazardous Substances Data)

Upstream product

• 495-76-1 piperonol 
• 2606-51-1 3,4-Methylenedioxybenzyl bromide 
• 106565-71-3 (3S,5R,8aS)-3-phenylhexahydro-2H-oxazolo[3,2-a]pyridine-5-carbonitrile 
• 88056-92-2 (-)-2-cyano-6-phenyloxazolopiperidine 

Downstream Products

• 135241-36-0 ((S)-2-Benzo[1,3]dioxol-5-ylmethyl-piperidin-1-yl)-(3,4,5-trimethoxy-phenyl)-methanone 
• 135241-36-0 ((R)-2-Benzo[1,3]dioxol-5-ylmethyl-piperidin-1-yl)-(3,4,5-trimethoxy-phenyl)-methanone 
• 135241-34-8 (S)-2-((S)-2-Benzo[1,3]dioxol-5-ylmethyl-piperidin-1-yl)-2-phenyl-ethanol 
• 135241-34-8 (R)-2-((R)-2-Benzo[1,3]dioxol-5-ylmethyl-piperidin-1-yl)-2-phenyl-ethanol 

Relevant articles and documents

Asymmetric Synthesis XXIV. Benzoquinolizidine Analogues of Podophyllotoxin via CN(R,S) Method.

The alkylation of 2-cyano-6-phenyloxazolopiperidin synthon 1 gave after reduction, the optically active pivotal amine 4.Bischler-Napieralski reaction of different aryl amides derived from 4 furnished the podophyllotoxin analogues 7, 8, and 9 after NaBH4 r