135275-62-6

Basic information

• Product Name: 5-(4-Chloro-phenyl)-2-(5-nitro-thiazol-2-yl)-2H-pyrazol-3-ylamine
• CAS NO: 135275-62-6
• Molecular Weight: 321.747
• Mol File: 135275-62-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(4-Chloro-phenyl)-2-(5-nitro-thiazol-2-yl)-2H-pyrazol-3-ylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(4-Chloro-phenyl)-2-(5-nitro-thiazol-2-yl)-2H-pyrazol-3-ylamine(135275-62-6)
• EPA Substance Registry System: 5-(4-Chloro-phenyl)-2-(5-nitro-thiazol-2-yl)-2H-pyrazol-3-ylamine(135275-62-6)

Safety Data

• Hazardous Substances Data: 135275-62-6(Hazardous Substances Data)

Upstream product

• 26245-59-0 2-hydrazino-5-nitrothiazole 
• 4640-66-8 p-chlorobenzoylacetonitrile 

Relevant articles and documents

Synthesis of some 2-heterocyclyl-5-nitrothiazoles as potential anthelmintics

Three series of 5-nitrothiazoles, namely 2-(3,5-dimethylpyrazol-1-yl)-5-nitrothiazoles (I), 2-(5-amino-3-arylpyrazol-1-yl)-5-nitrothiazoles (II) and 2-(5-nitrothiazol-2-yl)-6-aryl-4,5-dihydro-3(2H)-pyridazinones (III) and their 4-methyl analogues have been synthesized as potential anthelmintics by treatment of 2-hydrazino-5-nitrothiazoles with pentane-2,4-diones, α-cyanoacetophenones and β-aroylpropionic acids, respectively.None of the nine selected compounds tested shows any significant activity against N. brasiliensis and H. nana in mice at 250 mg/kg*3 days.Some of the compounds, however, show high antifungal activity.