1353013-43-0

Basic information

• Product Name: 3-(heptadec-1-yn-1-yl)-1-(p-tolyl)-1H-pyrrole-2,5-dione
• Synonyms: 3-(heptadec-1-yn-1-yl)-1-(p-tolyl)-1H-pyrrole-2,5-dione
• CAS NO: 1353013-43-0
• Molecular Weight: 421.623
• Mol File: 1353013-43-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-(heptadec-1-yn-1-yl)-1-(p-tolyl)-1H-pyrrole-2,5-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(heptadec-1-yn-1-yl)-1-(p-tolyl)-1H-pyrrole-2,5-dione(1353013-43-0)
• EPA Substance Registry System: 3-(heptadec-1-yn-1-yl)-1-(p-tolyl)-1H-pyrrole-2,5-dione(1353013-43-0)

Safety Data

• Hazardous Substances Data: 1353013-43-0(Hazardous Substances Data)

Upstream product

• 91182-54-6 3-bromo-1-(p-tolyl)-1H-pyrrole-2,5-dione 
• 26186-00-5 1-heptadecyne 

Relevant articles and documents

Sonogashira coupling reactions of bromomaleimides: Route to alkyne/cis-alkene/alkyl maleimides: Synthesis of luffarin X and cacospongionolide C

Palladium-catalyzed Sonogashira coupling reaction of bromomaleimides with a diverse range of terminal alkynes has been demonstrated to furnish the corresponding alkynylmaleimides in very good yields. This coupling reaction followed by selective reduction of the triple bond to single bond have been utilized as the decisive steps to accomplish the first total synthesis of natural products (±)-luffarin X and (±)-cacospongionolide C.