135427-08-6 Usage
Description
4-Fluoro-3-methylbenzaldehyde is an organic compound that serves as a crucial intermediate in various chemical syntheses. It is characterized by its yellow-greenish appearance, either in a liquid or low melting solid state, and plays a significant role in the production of various products across different industries.
Uses
Used in Organic Synthesis:
4-Fluoro-3-methylbenzaldehyde is used as a key intermediate for the synthesis of complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable component in the creation of a wide range of compounds.
Used in Pharmaceutical Industry:
In the pharmaceutical sector, 4-Fluoro-3-methylbenzaldehyde is utilized as a building block for the development of new drugs. Its properties enable the design of molecules with specific biological activities, contributing to the advancement of medicinal chemistry.
Used in Agrochemicals:
4-Fluoro-3-methylbenzaldehyde is employed as a vital component in the formulation of agrochemicals, such as pesticides and herbicides. Its incorporation into these products enhances their effectiveness in protecting crops and managing pests.
Used in Dye Stuff Field:
In the dye stuff industry, 4-Fluoro-3-methylbenzaldehyde is used as a raw material for the production of various dyes and pigments. Its chemical properties contribute to the development of dyes with specific color characteristics and improved performance.
Check Digit Verification of cas no
The CAS Registry Mumber 135427-08-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,4,2 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 135427-08:
(8*1)+(7*3)+(6*5)+(5*4)+(4*2)+(3*7)+(2*0)+(1*8)=116
116 % 10 = 6
So 135427-08-6 is a valid CAS Registry Number.
InChI:InChI=1/C11H7F3N2O4/c1-20-10(17)8(5-15)7-3-2-6(11(12,13)14)4-9(7)16(18)19/h2-4,8H,1H3
135427-08-6Relevant articles and documents
A Fluorinated Ligand Enables Room-Temperature and Regioselective Pd-Catalyzed Fluorination of Aryl Triflates and Bromides
Sather, Aaron C.,Lee, Hong Geun,De La Rosa, Valentina Y.,Yang, Yang,Müller, Peter,Buchwald, Stephen L.
supporting information, p. 13433 - 13438 (2015/11/09)
A new biaryl monophosphine ligand (AlPhos, L1) allows for the room-temperature Pd-catalyzed fluorination of a variety of activated (hetero)aryl triflates. Furthermore, aryl triflates and bromides that are prone to give mixtures of regioisomeric aryl fluorides with Pd-catalysis can now be converted to the desired aryl fluorides with high regioselectivity. Analysis of the solid-state structures of several Pd(II) complexes, as well as density functional theory (DFT) calculations, shed light on the origin of the enhanced reactivity observed with L1.
Piperazine derivatives
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Page/Page column 25, (2010/02/15)
This invention relates to piperazine derivatives of the formula: wherein each symbol is as defined in the description, and its pharmaceutically acceptable salt, to processes for preparation thereof, to pharmaceutical composition comprising the same, and to a use of the same for treating or preventing Tachykinin-mediated diseases in human being or animals.
Process for preparing benzyl alcohols and their use
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, (2008/06/13)
Benzyl alcohols, particularly those which bear fluorine substituents or fluoroalkyl substituents on the benzyl ring, can be obtained by formylation of corresponding aryl bromides to form benzaldehydes and reduction of the latter using further formate, wherein the benzaldehydes formed do not have to be isolated.
