135439-84-8

Basic information

• Product Name: p-nitrobenzyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-2-trifluoromethylsulphonyloxy-carbapen-2-em-3carboxylate
• Synonyms: p-nitrobenzyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-2-trifluoromethylsulphonyloxy-carbapen-2-em-3carboxylate
• CAS NO: 135439-84-8
• Molecular Weight: 480.375
• Mol File: 135439-84-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: p-nitrobenzyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-2-trifluoromethylsulphonyloxy-carbapen-2-em-3carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: p-nitrobenzyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-2-trifluoromethylsulphonyloxy-carbapen-2-em-3carboxylate(135439-84-8)
• EPA Substance Registry System: p-nitrobenzyl (5R,6S)-6-[(1R)-1-hydroxyethyl]-2-trifluoromethylsulphonyloxy-carbapen-2-em-3carboxylate(135439-84-8)

Safety Data

• Hazardous Substances Data: 135439-84-8(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 75363-99-4 4-nitrobenzyl (2R,5R,6S)-6-[(1R)-1-hydroxyethyl]-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylate 
• 74288-40-7 (5R,6S)-6-[(R)-1-hydroxyethyl]-3,7-dioxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid p-nitrobenzyl ester 
• 74288-40-7 (5R,6S)-6-(1-Hydroxy-ethyl)-3,7-dioxo-1-aza-bicyclo[3.2.0]heptane-2-carboxylic acid 4-nitro-benzyl ester 

Downstream Products

• 165743-30-6 p-nitrobenzyl (5R,6S)-6-[(1R)-hydroxyethyl]-2-(1-phenylpyrazol-3-yl)-carbapen-2-em-3-carboxylate 
• 1025902-20-8 (5R,6S)-6-((R)-1-Hydroxy-ethyl)-7-oxo-3-thiazol-5-yl-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 253268-65-4 3-[4-(N,N-dimethyl-carbamimidoyl)-dibenzofuran-2-yl]-7-oxo-6-(1-trimethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 
• 253268-64-3 (5R,6S)-3-[4-(N-Methylcarbamimidoyl)-dibenzofuran-2-yl]-7-oxo-6-((R)-1-trimethylsilanyloxy-ethyl)-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid 4-nitro-benzyl ester 

Relevant articles and documents

The synthesis and anti-MRSA activity of amidinium-substituted 2-dibenzofuranylcarbapenems

A series of amidinium-substituted 2-dibenzofuranylcarbapenems with potent activity against MRSA has been synthesized via a Stille cross-coupling reaction. These new carbapenems show reduced serum protein binding and improved in vivo efficacy as a conseque

A facile transformation of bicyclic keto esters to bisprotected (±)-8-epithienamycin via enol activation

A facile "one-pot" transformation of bicyclic keto ester (2) to bisprotected (±)-8-epithienamycin via enol phosphate activation followed by the addition-elimination reaction of N-protected cysteamine derivative is described.