13544-84-8 Usage
Description
(2,5-Dimethylbenzyl)(triphenyl)phosphorane is a phosphorane, an organophosphorus compound with the molecular formula C23H21P. It features a 2,5-dimethylbenzyl group and a triphenylphosphine group attached to the phosphorous atom. Phosphoranes are recognized for their role as reagents in organic synthesis, especially in the formation of carbon-carbon bonds.
Uses
Used in Organic Synthesis:
(2,5-Dimethylbenzyl)(triphenyl)phosphorane is used as a reagent for the formation of carbon-carbon bonds in organic synthesis. Its specific reactivity and chemical behavior make it a valuable component in creating complex organic molecules and structures.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, (2,5-Dimethylbenzyl)(triphenyl)phosphorane is used as a synthetic intermediate for the development of various pharmaceutical compounds. Its ability to form carbon-carbon bonds aids in the synthesis of complex drug molecules, contributing to the discovery and production of new medications.
Used in Chemical Research:
(2,5-Dimethylbenzyl)(triphenyl)phosphorane is also utilized in chemical research as a tool to study the properties and reactions of phosphoranes. Understanding its reactivity can lead to advancements in the field of organophosphorus chemistry and the development of new synthetic methods and applications.
Check Digit Verification of cas no
The CAS Registry Mumber 13544-84-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,4 and 4 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 13544-84:
(7*1)+(6*3)+(5*5)+(4*4)+(3*4)+(2*8)+(1*4)=98
98 % 10 = 8
So 13544-84-8 is a valid CAS Registry Number.
InChI:InChI=1/C27H26P/c1-22-18-19-23(2)24(20-22)21-28(25-12-6-3-7-13-25,26-14-8-4-9-15-26)27-16-10-5-11-17-27/h3-20H,21H2,1-2H3/q+1
13544-84-8Relevant articles and documents
Kinetic Study of the Substitution Reactions of Triphenylphosphine with Chlorobenzyl Chlorides, Dimethylbenzyl Chloride, and Methylbenzyl Bromides in Various Two-Phase Organic Solvent/Water Media
Shieh, Ruey-Lone,Lin, Ruey-Lih,Hwang, Jiann-Jyh,Jwo, Jing-Jer
, p. 517 - 523 (1998)
The kinetics of the substitution reactions of triphenylphosphine (TP) with chlorobenzyl chlorides (CBC), 2,5-dimethylbenzyl chloride (DMBC), and methylbenzyl bromides (MBB) in aprotic organic solvent was studied under the extraction by water. The effects of water, agitation, organic solvent, reactant, and temperature were investigated. These reactions take place via the SN2 mechanism and exhibit large and negative entropy of activation. The order of relative activity of solvents is CHCl3 > CH2Cl2 >> C6H6. In CHCl3, the order of relative reactivity of benzyl chloride (BC), benzyl bromide (BB), CBC, DMBC, and MBB toward reaction with TP is 2-MBB > 4-MBB > 3-MBB > BB > DMBC > BC > 2-CBC > 4-CBC > 3-CBC. These reactions produce quantitatively benzyltriphenylphosphonium salts, which are useful for synthesizing Z-form isomers of stilbenes via the two-phase Wittig reaction.
