13547-70-1 Usage
Description
1-Chloropinacolone, also known as 1-chloro-2-methoxypropanone, is an organic compound with the molecular formula C4H7ClO. It is a clear, slightly yellow liquid at room temperature and is commonly used as a synthetic intermediate in the production of various chemical compounds due to its reactive nature.
Uses
1. Used in Pharmaceutical Industry:
1-Chloropinacolone is used as an intermediate for the synthesis of triazole compounds, which possess significant biological activities. These triazole compounds are known for their antiviral, antibacterial, antifungal, and antituberculous properties, making them valuable in the development of new drugs and treatments for various diseases and infections.
2. Used in Chemical Synthesis:
1-Chloropinacolone serves as a versatile building block in the synthesis of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and functional group compatibility make it a popular choice for chemists working on the development of new molecules with potential applications in various industries.
3. Used in Research and Development:
In addition to its applications in the pharmaceutical and chemical industries, 1-Chloropinacolone is also utilized in research and development settings. Scientists and researchers use this compound to explore new reaction pathways, develop novel synthetic methods, and investigate the properties of related compounds, ultimately contributing to the advancement of chemical knowledge and innovation.
Hazard
A poison by ingestion. Low toxicity byinhalation.
Check Digit Verification of cas no
The CAS Registry Mumber 13547-70-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,3,5,4 and 7 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 13547-70:
(7*1)+(6*3)+(5*5)+(4*4)+(3*7)+(2*7)+(1*0)=101
101 % 10 = 1
So 13547-70-1 is a valid CAS Registry Number.
InChI:InChI=1/C6H11ClO/c1-6(2,3)5(8)4-7/h4H2,1-3H3
13547-70-1Relevant articles and documents
Fahey,Zuech
, p. 3276 (1974)
Simple and efficient methods for selective preparation of α-mono or α,α-dichloro ketones and β-ketoesters by using DCDMH
Chen, Zizhan,Zhou, Bin,Cai, Huihua,Zhu, Wei,Zou, Xinzhuo
experimental part, p. 275 - 278 (2010/04/22)
New processes that can selectively prepare α-mono or α,α-dichloro ketones and β-ketoesters using 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) are reported. Using silica gel as the catalyst and methanol as the solvent and heating for 1 h under reflux, α-monochlorinated products were selectively obtained in 86-98% yield. However using a deep eutectic solvent (choline chloride: p-TsOH = 1:1) as the solvent and stirring for 45 min at room temperature, α,α- dichlorinated products were selectively obtained in 86-95% yield.
Selective halogenation of ketones
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Page 3, (2008/06/13)
The present invention provides a process and apparatus for selectively halogenating a ketone of the formula (I) wherein R represents unsubstituted or halogen-substituted C1-C16-alkyl, or aryloxy, R1, R2 and R3 independently represent hydrogen, halogen, C1-C16-alkyl or aryl, the process involving heating the ketone to reflux in a reaction vessel such that the ketone vapor contacts a condensor attached to the reaction vessel and condenses, reacting the condensed ketone with halogen gas, and collecting the selectively halogenated ketone in the reaction vessel.
