1354714-48-9

Basic information

• Product Name: C₂₆H₂₂N₄O₂
• Synonyms: C₂₆H₂₂N₄O₂
• CAS NO: 1354714-48-9
• Molecular Weight: 422.486
• Mol File: 1354714-48-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: C₂₆H₂₂N₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₂₂N₄O₂(1354714-48-9)
• EPA Substance Registry System: C₂₆H₂₂N₄O₂(1354714-48-9)

Safety Data

• Hazardous Substances Data: 1354714-48-9(Hazardous Substances Data)

Upstream product

• 776-41-0 indole-3-carboxylic acid ethyl ester 
• 771-50-6 1H-indole-3-carboxylic acid 
• 15317-58-5 1H-indole-3-carboxylic acid hydrazide 
• 928835-08-9 1-[(4-methoxyphenyl)methyl]-1H-indole-3-carboxaldehyde 
• 487-89-8 Indole-3-carboxaldehyde 
• 120-72-9 indole 

Downstream Products

• 1431138-10-1 C₂₆H₂₀N₄O₂ 

Relevant articles and documents

Novel bis(indolyl)hydrazide-hydrazones as potent cytotoxic agents

A series of bis(indolyl) hydrazide-hydrazones 5a-n were synthesized and evaluated for their cytotoxicity against selected human cancer cell lines. The reaction of indole-3-carboxaldehyde 2 with indole-3-carbohydrazide 4 in presence of catalytic amount of acetic acid afforded 5a-n in good yields. Among the synthesized bis(indolyl)hydrazide-hydrazones, the compound 5b with N-(p-chlorobenzyl) and bromo substituents was found to be the most potent against multiple cancer cell lines (IC50 = 1.0 μM, MDA-MB-231). The compound 5k exhibited selective cytotoxicity against breast cancer cell line MCF7 (IC50 = 3.1 μM).