1354834-17-5

Basic information

• Product Name: 1-(3-bromo-4-methoxyphenyl)hept-6-en-3-one
• Synonyms: 1-(3-bromo-4-methoxyphenyl)hept-6-en-3-one
• CAS NO: 1354834-17-5
• Molecular Weight: 297.192
• Mol File: 1354834-17-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(3-bromo-4-methoxyphenyl)hept-6-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(3-bromo-4-methoxyphenyl)hept-6-en-3-one(1354834-17-5)
• EPA Substance Registry System: 1-(3-bromo-4-methoxyphenyl)hept-6-en-3-one(1354834-17-5)

Safety Data

• Hazardous Substances Data: 1354834-17-5(Hazardous Substances Data)

Upstream product

• 1857-57-4 3-(3-bromo-4-methoxyphenyl)propionic acid 
• 15823-04-8 methyl 3-(4-methoxyphenyl)propionate 
• 1354834-15-3 3-(3-bromo-4-methoxyphenyl)-N-methoxy-N-methylpropanamide 
• 7103-09-5 4-but-1-enylmagnesium bromide 
• 288310-70-3 3-(3-bromo-4-methoxyphenyl)-propionic acid methyl ester 

Downstream Products

• 1330753-47-3 1-(3-bromo-4-methoxyphenyl)-7-(3-methoxy-4-hydroxyphenyl)heptan-3-one 
• 1330753-35-9 1-(3-bromo-4-methoxyphenyl)-7-(3-hydroxy-4-methoxyphenyl)heptan-3-one 
• 1354834-20-0 (E)-1-(3-bromo-4-methoxyphenyl)-7-(3-hydroxy-4-methoxyphenyl)hept-6-en-3-one 
• 1354834-19-7 (E)-7-(4-(benzyloxy)-3-methoxyphenyl)-1-(3-bromo-4-methoxyphenyl)hept-6-en-3-one 

Relevant articles and documents

Synthesis and evaluation of macrocyclic diarylether heptanoid natural products and their analogs

The macrocyclic diarylether heptanoid (MDEH) natural products have been used in folk medicine for centuries. MDEHs are reported to exert anti-tumor properties by inhibiting the activation of NF-κB. Here we report the synthesis of a small MDEH library (first reported synthesis of racemic platycarynol) using a Grubbs cross metathesis/Ullmann cyclization strategy. Evaluation of the library led to the identification of MDEH 9b which sensitizes pancreatic cancer cells to gemcitabine mediated growth inhibition and apoptosis.