1356930-86-3Relevant articles and documents
Direct transformation of 5-hydroxymethylfurfural to the building blocks 2,5-dihydroxymethylfurfural (DHMF) and 5-hydroxymethyl furanoic acid (HMFA) via Cannizzaro reaction
Subbiah, Sowmiah,Simeonov, Svilen P.,Esperanca, Jose M. S. S.,Rebelo, Luis Paulo N.,Afonso, Carlos A. M.
, p. 2849 - 2853 (2013)
An efficient, simple, scalable and atom efficient method for the synthesis of 2,5-dihydroxymethylfuran (DHMF) and 5-hydroxymethylfuranoic acid, as sodium salt (HMFA), in 80% yield from 5-hydroxymethylfurfural (HMF) in water using NaOH (0.9 eq.) via a Cannizzaro reaction is described. Both the building blocks DHMF and HMFA were successfully isolated merely using selective crystallisation.
