135721-98-1 Usage
Uses
S 14506 is a full, highly potent and selective SR-1A agonist.
Biological Activity
Highly potent selective 5-HT 1A receptor full agonist (pK i values are 9.0, 6.6, 7.5, 6.6 and < 6.0 for 5-HT 1A , 5-HT 1B , 5-HT 1C , 5-HT 2 and 5-HT 3 receptors respectively). Possibly binds between the agonist binding site and the G protein interaction switch site, affecting the activation mechanism, and may display positive cooperativity. Anxiolytic following central administration in vivo .
Check Digit Verification of cas no
The CAS Registry Mumber 135721-98-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,3,5,7,2 and 1 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 135721-98:
(8*1)+(7*3)+(6*5)+(5*7)+(4*2)+(3*1)+(2*9)+(1*8)=131
131 % 10 = 1
So 135721-98-1 is a valid CAS Registry Number.
InChI:InChI=1/C24H26FN3O2.ClH/c1-30-21-10-7-18-3-2-4-23(22(18)17-21)28-15-13-27(14-16-28)12-11-26-24(29)19-5-8-20(25)9-6-19;/h2-10,17H,11-16H2,1H3,(H,26,29);1H