1357917-76-0

Basic information

• Product Name: 2-benzylideneamino-N,N-dimethylacetamide
• Synonyms: 2-benzylideneamino-N,N-dimethylacetamide
• CAS NO: 1357917-76-0
• Molecular Weight: 190.245
• Mol File: 1357917-76-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-benzylideneamino-N,N-dimethylacetamide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-benzylideneamino-N,N-dimethylacetamide(1357917-76-0)
• EPA Substance Registry System: 2-benzylideneamino-N,N-dimethylacetamide(1357917-76-0)

Safety Data

• Hazardous Substances Data: 1357917-76-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 72287-77-5 2-amino-N,N-dimethyl-acetamide hydrochloride 
• 1857-19-8 N',N'-dimethylglycinamide 

Downstream Products

• 1357917-61-3 (1R,3S,3aS,6aR)-5-methyl-4,6-dioxo-3-phenyl-octahydropyrrolo[3,4-c]pyrrole-1-N,N-dimethylcarboxamide 
• 1357917-96-4 (2R,3R,4S,5R)-4-nitro-3,5-diphenylpyrrolidine-2-N,N-dimethylcarboxamide 
• 1357917-94-2 (2R,4S,5R)-5-phenyl-4-(phenylsulfonyl)pyrrolidine-2-N,N-dimethylcarboxamide 
• 1357918-01-4 (2R,3R,4S,5S)-dimethyl 2-(dimethylcarbamoyl)-5-phenylpyrrolidine-3,4-dicarboxylate 
• 1357918-00-3 (2R,3S,4S,5S)-dimethyl 2-(dimethylcarbamoyl)-5-phenylpyrrolidine-3,4-dicarboxylate 

Relevant articles and documents

Boron Dipyrromethene (BODIPY) as Electron-Withdrawing Group in Asymmetric Copper-Catalyzed [3+2] Cycloadditions for the Synthesis of Pyrrolidine-Based Biological Sensors

In this work, we describe the use of Boron Dipyrromethene (BODIPY) as electron-withdrawing group for activation of double bonds in asymmetric copper-catalyzed [3+2] cycloaddition reactions with azomethine ylides. The reactions take place under smooth conditions and with high enantiomeric excess for a large number of different substituents, pointing out the high activation of the alkene by using a boron dipyrromethene as electron-withdrawing group. Experimental, theoretical studies and comparison with other common electron-withdrawing groups in asymmetric copper-catalyzed [3+2] cycloadditions show the reasons of the different reactivity of the boron dipyrromethene derivatives, which can be exploited as a useful activating group in asymmetric catalysis. Additional experiments show that the so obtained pyrrolidines can be employed as biocompatible biosensors, which can be located in the endosomal compartments and do not present toxicity in three cell lines. (Figure presented.).