135829-03-7Relevant articles and documents
Aldolase-catalyzed synthesis of conformationally constrained iminocyclitols: Preparation of polyhydroxylated benzopyrrolizidines and cyclohexapyrrolizidines
Laborda, Pedro,Sayago, Francisco J.,Cativiela, Carlos,Parella, Teodor,Joglar, Jesus,Clapes, Pere
supporting information, p. 1422 - 1425 (2014/04/03)
A straightforward chemo-enzymatic synthesis of new polyhydroxylated benzopyrrolizidines and cyclohexapyrrolizidines is developed. The two-step strategy consists of l-fuculose-1-phosphate aldolase variant F131A-catalyzed aldol addition of dihydroxyacetone phosphate to rac-N-benzyloxycarbonylindoline- 2-carbaldehyde as well as (2S*,3aS*,7aS*)- and (2S*,3aR*,7aR*)-N-benzyloxycarbonyloctahydroindole-2- carbaldehydes and a subsequent one-step catalytic deprotection-reductive amination.
On the origins of enantioselectivity in oxazaborolidine mediated carbonyl reductions
Jones, Graham B.,Heaton, Steven B.,Chapman, Brant J.,Guzel, Mustafa
, p. 3625 - 3636 (2007/10/03)
A series of tricyclic oxazaborolidine catalysts have been prepared from readily available (S)-indoline-2-carboxylic acid. In each case, an arene chromium(0) carbonyl group was introduced on one face of the catalyst. Results obtained in the borane mediated
